The 1920 United States Senate election in North Carolina was held on November 2, 1920. Incumbent Democratic Senator Lee Slater Overman was re-elected to a fourth term in office, defeating Republican A. E. Holton.
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| Party | Candidate | Votes | % | |
|---|---|---|---|---|
| Democratic | Lee Slater Overman (incumbent) | 94,806 | 79.89% | |
| Democratic | Aubrey L. Brooks | 23,869 | 20.11% | |
| Total votes | 118,675 | 100.00% | ||
| Party | Candidate | Votes | % | |
|---|---|---|---|---|
| Democratic | Lee Slater Overman (Incumbent) | 310,504 | 57.52% | |
| Republican | A. Eugene Holton | 229,343 | 42.48% | |
| Majority | 81,161 | 15.04% | ||
| Turnout | 539,847 | |||
| Democratic hold | ||||
