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Acefylline





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Acefylline (INN),[1] also known as 7-theophyllineacetic acid, is a stimulant drug of the xanthine chemical class. It acts as an adenosine receptor antagonist. It is combined with diphenhydramine in the pharmaceutical preparation etanautine to help offset diphenhydramine induced drowsiness.[2]

Acefylline
Skeletal formula of acefylline
Ball-and-stick model of the acefylline molecule
Clinical data
Routes of
administration
Intramuscular, Intravenous
ATC code
Identifiers
  • (1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetic acid

CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.010.447 Edit this at Wikidata
Chemical and physical data
FormulaC9H10N4O4
Molar mass238.203 g·mol−1
3D model (JSmol)
  • O=C2N(c1ncn(c1C(=O)N2C)CC(=O)O)C

  • InChI=1S/C9H10N4O4/c1-11-7-6(8(16)12(2)9(11)17)13(4-10-7)3-5(14)15/h4H,3H2,1-2H3,(H,14,15) checkY

  • Key:HCYFGRCYSCXKNQ-UHFFFAOYSA-N checkY

  (verify)

Asilanolmannuronic acid conjugate of acefylline, acefylline methylsilanol mannuronate (INCI; trade name Xantalgosil C) is marketed as a lipolytic phosphodiesterase inhibitor. It is used as an ingredient in cosmeceuticals for the treatment of cellulite and as a skin conditioner.[3][4]

See also

edit

References

edit
  1. ^ "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names (Rec. INN): List 21" (PDF). World Health Organization. Retrieved 29 December 2016.
  • ^ Zuidema J (1978). "Biofarmaceutische en farmacokinetische aspecten van theofylline en acefylline". Thesis (doctoral)--Universiteit van Amsterdam. Archived from the original on 2016-12-30. Retrieved 2012-09-29. {{cite journal}}: Cite journal requires |journal= (help)
  • ^ Biosil Technologies (2005). "Xantalgosil C® Datasheet" (PDF). Exsymol S.A.M. Retrieved 2022-01-20.
  • ^ Winter, Ruth (2009-10-20). A Consumer's Dictionary of Cosmetic Ingredients (7th ed.). Harmony/Rodale. p. 42. ISBN 9780307459862.

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  • Retrieved from "https://en.wikipedia.org/w/index.php?title=Acefylline&oldid=1202423701"
     



    Last edited on 2 February 2024, at 18:55  





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    This page was last edited on 2 February 2024, at 18:55 (UTC).

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