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Research continues into the best imaging method for detecting and staging endometrial cancer. As current diagnostic methods are invasive and inaccurate, researchers are looking into new ways to catch endometrial cancer, especially in its early stages. A study found that using a technique involving [[Infrared|infrared light]] on simple blood test samples detected uterine cancer with high accuracy (87%), and could detect [[Precancerous condition|precancerous growths]] in all cases.<ref>{{Cite journal |date=2020-11-12 |title=Womb cancer could be detected early with an inexpensive new blood test |url=https://evidence.nihr.ac.uk/alert/womb-cancer-could-be-detected-early-with-an-inexpensive-new-blood-test/ |journal=NIHR Evidence |type=Plain English summary |language=en |doi=10.3310/alert_42575|s2cid=241679195 }}</ref><ref>{{Cite journal |last1=Paraskevaidi |first1=Maria |last2=Morais |first2=Camilo L. M. |last3=Ashton |first3=Katherine M. |last4=Stringfellow |first4=Helen F. |last5=McVey |first5=Rhona J. |last6=Ryan |first6=Neil A. J. |last7=O'Flynn |first7=Helena |last8=Sivalingam |first8=Vanitha N. |last9=Kitson |first9=Sarah J. |last10=MacKintosh |first10=Michelle L. |last11=Derbyshire |first11=Abigail E. |date=2020-05-16 |title=Detecting Endometrial Cancer by Blood Spectroscopy: A Diagnostic Cross-Sectional Study |journal=Cancers |language=en |volume=12 |issue=5 |pages=1256 |doi=10.3390/cancers12051256 |issn=2072-6694 |pmc=7281323 |pmid=32429365|doi-access=free }}</ref> In surgery, research has shown that complete pelvic lymphadenectomy along with hysterectomy in stage 1 endometrial cancer does not improve survival and increases the risk of negative side effects, including lymphedema. Other research is exploring the potential of identifying the [[sentinel lymph node]]s for biopsy by injecting the tumor with dye that shines under [[infrared]] light. [[Intensity modulated radiation therapy]] is currently under investigation, and already used in some centers, for application in endometrial cancer, to reduce side effects from traditional radiotherapy. Its risk of recurrence has not yet been quantified. Research on [[hyperbaric oxygen therapy]] to reduce side effects is also ongoing. The results of the PORTEC 3 trial assessing combining adjuvant radiotherapy with chemotherapy were awaited in late 2014.<ref name=CRUKresearch/>
There is not enough evidence to determine if people with endometrial cancer benefit from additional behavioural and life style interventions that are aimed at losing excess weight.<ref>{{cite journal | vauthors = Kitson S, Ryan N, MacKintosh ML, Edmondson R, Duffy JM, Crosbie EJ | title = Interventions for weight reduction in obesity to improve survival in women with endometrial cancer | journal = The Cochrane Database of Systematic Reviews | volume = 2018 | pages = CD012513 | date = February 2018 | issue = 2 | pmid = 29388687 | pmc = 6491136 | doi = 10.1002/14651858.CD012513.pub2 | url = https://www.research.manchester.ac.uk/portal/en/publications/interventions-for-weight-reduction-in-obesity-to-improve-survival-in-women-with-endometrial-cancer(bc38a044-90f0-4479-9323-af2e7f95e824).html }}</ref>{{Update inline|reason=Updated version https://www.ncbi.nlm.nih.gov/pubmed/36971688|date = April 2023}}
==History and culture==
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