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{{see also|Thyroid disease in pregnancy}}
Recognizing and evaluating hyperthyroidism in pregnancy is a diagnostic challenge.<ref>{{cite journal | vauthors = Fumarola A, Di Fiore A, Dainelli M, Grani G, Carbotta G, Calvanese A | title = Therapy of hyperthyroidism in pregnancy and breastfeeding | journal = Obstetrical & Gynecological Survey | volume = 66 | issue = 6 | pages = 378–385 | date = June 2011 | pmid = 21851752 | doi = 10.1097/ogx.0b013e31822c6388 | s2cid = 28728514 }}</ref> Thyroid hormones are commonly elevated during the first trimester of pregnancy as the pregnancy hormone [[human chorionic gonadotropin]] (hCG) stimulates thyroid hormone production, in a condition known as gestational transient thyrotoxicosis.<ref name="Lee 2023" />
Propylthiouracil is the preferred [[antithyroid]] medication in the 1st trimester of pregnancy as it is less [[teratogenic]] than methimazole.<ref name="Lee 2023" />
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