The Reissert reaction is a series of chemical reactions that transforms quinolinetoquinaldic acid.[1][2] Quinolines will react with acid chlorides and potassium cyanide to give 1-acyl-2-cyano-1,2-dihydroquinolines, also known as Reissert compounds. Hydrolysis gives the desired quinaldic acid.
| Reissert reaction | |
|---|---|
| Named after | Arnold Reissert |
| Reaction type | Addition reaction |
The Reissert reaction is also successful with isoquinolines[3][4] and most pyridines.
Several reviews have been published.[5][6]