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6-Isopropyl-6-nor-lysergic acid diethylamide





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(Redirected from IP-LAD)
 


6-Isopropyl-6-nor-lysergic acid diethylamide (IP-LAD) is an analogoflysergic acid diethylamide (LSD) developed by the team of David E. Nichols. In studies on mice, it was found to be approximately 40% the potency of LSD, compared to the 60% increase in potency seen with ETH-LAD, 2-fold potency increase of AL-LAD, and roughly equivalent potency of PRO-LAD.[1]

6-Isopropyl-6-nor-lysergic acid diethylamide
Clinical data
Routes of
administration
Oral
Legal status
Legal status
  • DE: NpSG (Industrial and scientific use only)
  • UK: Class A
  • Identifiers
    • (6aR,9R)-N,N-Diethyl-7-propan-2-yl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide

    PubChem CID
    ChemSpider
    ChEMBL
    Chemical and physical data
    FormulaC22H29N3O
    Molar mass351.494 g·mol−1
    3D model (JSmol)
    • CCN(CC)C(=O)[C@H]1CN([C@@H]2CC3=CNC4=CC=CC(=C34)C2=C1)C(C)C

    • InChI=1S/C22H29N3O/c1-5-24(6-2)22(26)16-10-18-17-8-7-9-19-21(17)15(12-23-19)11-20(18)25(13-16)14(3)4/h7-10,12,14,16,20,23H,5-6,11,13H2,1-4H3/t16-,20-/m1/s1

    • Key:GLNOSFGSNDKLOC-OXQOHEQNSA-N

      (verify)

    References

    edit
    1. ^ Hoffman AJ, Nichols DE (September 1985). "Synthesis and LSD-like discriminative stimulus properties in a series of N(6)-alkyl norlysergic acid N,N-diethylamide derivatives". Journal of Medicinal Chemistry. 28 (9): 1252–1255. doi:10.1021/jm00147a022. PMID 4032428.
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  • Retrieved from "https://en.wikipedia.org/w/index.php?title=6-Isopropyl-6-nor-lysergic_acid_diethylamide&oldid=1162373656"
     



    Last edited on 28 June 2023, at 18:26  





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    This page was last edited on 28 June 2023, at 18:26 (UTC).

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