RNR3 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | RNR3, RNA, ribosomal 45S cluster 3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 180452; GeneCards: RNR3; OMA:RNR3 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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RNA, ribosomal 3, also known as RNR3, is a human gene.[2] It is a minor isoform of large subunit of ribonucleotide-diphosphate reductase; the RNR complex catalyzes the rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits; RNR3 has a paralog, RNR1, that arose from the whole genome duplication.[3]
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