Contents

Chromone

Chromone

Names
IUPAC name Chromen-4-one
Preferred IUPAC name 4H-1-Benzopyran-4-one
Other names 4-Chromone; 1,4-Benzopyrone; 4H-Chromen-4-one; Benzo-gamma-pyrone; 1-Benzopyran-4-one; 4H-Benzo(b)pyran-4-one
Identifiers
CAS Number	491-38-3 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:72013 N
ChEMBL	ChEMBL13311 N
ChemSpider	9866 N
ECHA InfoCard	100.007.035
PubChem CID	10286
UNII	20C556MJ76 Y
CompTox Dashboard (EPA)	DTXSID40197680
InChI InChI=1S/C9H6O2/c10-8-5-6-11-9-4-2-1-3-7(8)9/h1-6H N Key: OTAFHZMPRISVEM-UHFFFAOYSA-N N InChI=1/C9H6O2/c10-8-5-6-11-9-4-2-1-3-7(8)9/h1-6H Key: OTAFHZMPRISVEM-UHFFFAOYAY
SMILES O=C1C=COc2ccccc12
Properties
Chemical formula	C9H6O2
Molar mass	146.145 g·mol−1
Acidity (pKa)	-2.0 (of conjugate acid)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

Chemical compound

Chromone (or1,4-benzopyrone) is a derivative of benzopyran with a substituted keto group on the pyran ring. It is an isomer of coumarin.

Derivatives of chromone are collectively known as chromones. Most, though not all, chromones are also phenylpropanoids.

• 6,7-dimethoxy-2,3-dihydrochromone has been isolated from Sarcolobus globosus.
• Eucryphin, a chromone rhamnoside, can be isolated from the bark of Eucryphia cordifolia.^[1]
• Cromolyn (disodium cromoglicate) was found to inhibit antigen challenge as well as stress induced symptoms.^[2] Cromoglicate is used as a mast cell stabilizerinallergic rhinitis, asthma and allergic conjunctivitis.
• Nedocromil sodium was found to have a somewhat longer half-life than cromolyn; however, production was discontinued in the US in 2008.
• Xanthone with a second aromatic ring.

• Coumarin – a structural isomer
• Furanochromones

• CID 10286 from PubChem – "4-chromone"
• Chromones at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
• Synthesis at organic-chemistry.org