Contents

Deltex e3 ubiquitin ligase 3

Protein-coding gene in humans

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DTX3
Identifiers
Aliases	DTX3, RNF154, deltex3, deltex 3, E3 ubiquitin ligase, deltex E3 ubiquitin ligase 3
External IDs	OMIM: 613142; MGI: 2135752; HomoloGene: 12754; GeneCards: DTX3; OMA:DTX3 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q13.3 Start 57,604,622 bp[1] End 57,609,804 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 D3 Start 127,190,378 bp[2] End 127,195,728 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum anterior pituitary right frontal lobe right uterine tube endothelial cell left ovary body of uterus right ovary anterior cingulate cortex nucleus accumbens Top expressed in neural layer of retina superior frontal gyrus primary visual cortex dentate gyrus of hippocampal formation granule cell cerebellar cortex ventricular zone habenula dorsomedial hypothalamic nucleus piriform cortex spermatocyte More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding metal ion binding transferase activity zinc ion binding Cellular component cytoplasm Biological process Notch signaling pathway protein ubiquitination Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 196403 80904 Ensembl ENSG00000178498 ENSMUSG00000040415 UniProt Q8N9I9 Q80V91 RefSeq (mRNA) NM_001286245 NM_001286246 NM_178502 NM_030714 NM_001368332 RefSeq (protein) NP_001273174 NP_001273175 NP_848597 NP_109639 NP_001355261 Location (UCSC) Chr 12: 57.6 – 57.61 Mb Chr 10: 127.19 – 127.2 Mb PubMed search [3] [4]
Wikidata
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Probable E3 ubiquitin-protein ligase DTX3 is a protein that in humans is encoded by the DTX3 gene. ^[5]

Function[edit]

DTX3 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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