● Home ● Random ● Nearby ● Log in ● Settings ● Donate ● About Wikipedia ● Disclaimers

GPR33

● Article ● Talk ● Language ● Watch ● Edit

Probable G-protein coupled receptor 33 is a protein that in humans is encoded by the GPR33 gene.^[5]^[6]

GPR33

Identifiers

GPR33, G protein-coupled receptor 33 (gene/pseudogene), G protein-coupled receptor 33

External IDs

OMIM: 610118; MGI: 1277106; HomoloGene: 7345; GeneCards: GPR33; OMA:GPR33 - orthologs

Gene location (Human)

Chr.	Chromosome 14 (human)^[1]

Band	14q12	Start	31,482,875 bp^[1]
Band	14q12	End	31,488,039 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 12 (mouse)^[2]

Band	12\|12 C1	Start	52,069,786 bp^[2]
Band	12\|12 C1	End	52,074,846 bp^[2]

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

duodenum

white blood cell

appendix

monocyte

lymph node

tonsil

urinary bladder

left ventricle

salivary gland

Top expressed in

lumbar subsegment of spinal cord

right ventricle

central gray substance of midbrain

nucleus of stria terminalis

sternocleidomastoid muscle

upper arm

triceps brachii muscle

tracheobronchial tree

mucosa of small intestine

tibiofemoral joint

More reference expression data

n/a

Gene ontology
Molecular function	signal transducer activity complement receptor activity G protein-coupled receptor activity
Cellular component	integral component of membrane plasma membrane membrane integral component of plasma membrane
Biological process	G protein-coupled receptor signaling pathway signal transduction complement receptor mediated signaling pathway inflammatory response phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration leukocyte migration cell chemotaxis
Sources:Amigo / QuickGO

Species

Human

Mouse


2856


14762


ENSG00000214943


ENSMUSG00000035148


Q49SQ1


O88416

RefSeq (mRNA)


NM_001197184


NM_008159

RefSeq (protein)


NP_001184113 NP_001184113.2


NP_032185

Location (UCSC)

Chr 14: 31.48 – 31.49 Mb

Chr 12: 52.07 – 52.07 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000214943 – Ensembl, May 2017

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035148 – Ensembl, May 2017

^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

^ Marchese A, Nguyen T, Malik P, Xu S, Cheng R, Xie Z, Heng HH, George SR, Kolakowski LF Jr, O'Dowd BF (Oct 1998). "Cloning genes encoding receptors related to chemoattractant receptors". Genomics. 50 (2): 281–6. doi:10.1006/geno.1998.5297. PMID 9653656.

^ "Entrez Gene: GPR33 G protein-coupled receptor 33".

Further reading

Römpler H, Schulz A, Pitra C, et al. (2005). "The rise and fall of the chemoattractant receptor GPR33". J. Biol. Chem. 280 (35): 31068–75. doi:10.1074/jbc.M503586200. hdl:11858/00-001M-0000-0010-0286-5. PMID 15987686.

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

t

e

Retrieved from "https://en.wikipedia.org/w/index.php?title=GPR33&oldid=1193779269" Last edited on 5 January 2024, at 16:18

Languages

●Српски / srpski ●Srpskohrvatski / српскохрватски ●Українська

●This page was last edited on 5 January 2024, at 16:18 (UTC). ●Content is available under CC BY-SA 4.0 unless otherwise noted. ●Privacy policy ●About Wikipedia ●Disclaimers ●Contact Wikipedia ●Code of Conduct ●Developers ●Statistics ●Cookie statement ●Terms of Use ●Desktop