Anisocytosis is a medical term meaning that a patient's red blood cells are of unequal size. This is commonly found in anemia and other blood conditions. False diagnostic flagging may be triggered on a complete blood count by an elevated WBC count, agglutinated RBCs, RBC fragments, giant platelets or platelet clumps. In addition, it is a characteristic feature of bovine blood.
| Anisocytosis | |
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| Human red blood cells from a case of anisocytosis. |
The red cell distribution width (RDW) is a measurement of anisocytosis[1] and is calculated as a coefficient of variation of the distribution of RBC volumes divided by the mean corpuscular volume (MCV).
Anisocytosis is identified by RDW and is classified according to the size of RBC measured by MCV. According to this, it can be divided into
Increased RDW is seen in iron deficiency anemia and decreased or normal in thalassemia major (Cooley's anemia), thalassemia intermedia
From Ancient Greek: an- without, or negative quality, iso- equal, cyt- cell, -osis condition.[3]
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