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Chelates in animal nutrition





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Chelates in animal feed is jargon for metalloorganic compounds added to animal feed. The compounds provide sources of various metals that improve the health or marketability of the animal. Typical metals salts are derived from cobalt, copper, iron, manganese, and zinc. The objective of supplementation with trace minerals is to avoid a variety of deficiency diseases. Trace minerals carry out key functions in relation to many metabolic processes, most notably as cofactors for enzymes and hormones, and are essential for optimum health, growth and productivity. For example, supplementary minerals help ensure good growth, bone development, feathering in birds, hoof, skin and hair quality in mammals, enzyme structure and functions, and appetite. Deficiency of trace minerals affect many metabolic processes and so may be manifested by different symptoms, such as poor growth and appetite, reproductive failures, impaired immune responses, and general ill-thrift. From the 1950s to the 1990s most trace mineral supplementation of animal diets was in the form of inorganic minerals, and these largely eradicated associated deficiency diseases in farm animals. The role in fertility and reproductive diseases of dairy cattle highlights that organic forms of Zn are retained better than inorganic sources and so may provide greater benefit in disease prevention, notably mastitis and lameness.

Structure of typical metal ion in the absence of chelate.

Animals are thought to better absorb, digest, and use mineral chelates than inorganic minerals or simple salts.[1] In theory lower concentrations of these minerals can be used in animal feeds. In addition, animals fed chelated sources of essential trace minerals excrete lower amounts in their faeces, and so there is less environmental contamination.

History and terminology

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Structure of a typical metal–edta chelate compound,[2] illustrating how the organic chelating agent (edta) wraps around the metal.

Since the 1950s, animal feeds have been supplemented with a variety of trace minerals such as copper (Cu), iron (Fe), iodine (I), manganese (Mn), molybdenum (Mo), selenium (Se), and zinc (Zn). Initially, such supplementation was in the form of inorganic salts of these trace elements, e.g. copper(II) sulfate. Chelated minerals were first developed in the early 1970s, but saw more growth in the 1980s and 1990s. Trace mineral chelates have been shown in some cases to be more efficient than inorganic minerals in meeting the nutritional needs of farm animals.[3] In some cases, chelates offer no advantage however.[4]

Terminology

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Chelates are incorporated into the feed.

Research

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Regulation

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The European Union is concerned about possible detrimental effects of excess supplementation with trace minerals on the environment or human and animal health, and in 2003 legislated a reduction in permitted feed concentrations of several trace metals (Co, Cu, Fe, Mn and Zn).[17]

Further reading

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References

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  1. ^ Richards, James D.; Fisher, Paula M.; Evans, Joseph L.; Wedekind, Karen J. (2015-06-25). "Greater bioavailability of chelated compared with inorganic zinc in broiler chicks in the presence or absence of elevated calcium and phosphorus". Open Access Animal Physiology. 7: 97–110. doi:10.2147/OAAP.S83845. Retrieved 2019-12-20.
  • ^ Solans, X.; Font Altaba, M.; García Oricain, J. (1984). "Crystal Structures of Ethylenediaminetetraacetato Metal Complexes. V. Structures Containing the [Fe(C10H12N2O8)(H2O)] Anion". Acta Crystallographica Section C. 40 (4): 635–638. doi:10.1107/S0108270184005151.
  • ^ (McCartney, 2008)
  • ^ Apgar, G. A.; Kornegay, E. T.; Lindemann, M. D.; Notter, D. R. (1995). "Evaluation of Copper Sulfate and a Copper Lysine Complex as Growth Promoters for Weanling Swine". Journal of Animal Science. 73 (9): 2640–2646. doi:10.2527/1995.7392640x. PMID 8582853.
  • ^ Soetan, K. O.; Olaiya, C. O.; Oyewole, O. E. (2010). "The importance of mineral elements for humans, domestic animals and plants - a review". -African Journal of Food Science. 4: 200–222.
  • ^ "Chelated Ingredients". Watson Inc. Retrieved 2019-12-20.
  • ^ quote by Du et al.,1996
  • ^ Z. Du, R.W. Hemken, J.A. Jackson and D.S. Trammell (1996) Utilization of copper in copper proteinate, copper lysine and cupric sulfate using the rat as an experimental model.Journal of animal science
  • ^ Sci. 81:161-171.
  • ^ J. P. Ryan, P. Kearns and T. Quinn (2002) Bioavailability of dietary copper and zinc in adult Texel sheep: A comparative study of the effects of sulfate and Bioplex supplementation. Irish Veterinary Journal
  • ^ M.S. Carlson, C.A. Boren, C.Wu, C.E. Huntington, D.W. Bollinger and T.L. Veum (2004) Evaluation of various inclusion rates of organic zinc either as polysaccharide or proteinate complex on the growth performance, plasma and excretion of nursery pigs. J. Anim. Science
  • ^ T.L. Veum, M.S. Carlson, C.W. Wu, D.W. Bollinger and M.R. Ellersieck (2004) Copper proteinate in weanling pig diets for enhancing growth performance and reducing fecal copper excretion compared with copper sulfate. J. Anim. Sci
  • ^ Y. Guo, Zhang, Yuan and W. Nie.et al., 2003, Effects of source and level of magnesium and Vitamin E on prevention of hepatic peroxidation and oxidative deterioration of broiler meat., Sci.Tech.
  • ^ T. Ao, J.L. Pierce, R. Power, K.A. Dawson, A.J. Pescatore, A.H. Cantor and M.J. Ford (2006) Investigation of relative bioavailability value and requirement of organic zinc for chicks. J. Poultry. Sci
  • ^ quote by Nollet et al.2007
  • ^ by Peric et al.2007
  • ^ Commission Regulation (EC) No 1334/2003 of 25 July 2003 amending the conditions for authorisation of a number of additives in feedingstuffs belonging to the group of trace elements. 26.7.2003 EN Official Journal of the E.U.
  • Topics of the works
  • SCAN (2003b), Opinion of the Scientific Committee for Animal Nutrition on the use of zinc in feedingstuffs.
  • Commission Regulation (EC) No 1334/2003 of 25 July 2003 amending the conditions for authorisation of a number of additives in feedingstuffs belonging to the group of trace elements. 26.7.2003 EN Official Journal of the European Union .
  • E. McCartney (2008) Trace minerals in poultry nutrition–sourcing safe minerals, organically? World Poultry
  • D. Wilde (2006). Influence of macro and micro minerals in the peri-parturient period on fertility in dairy cattle. Animal Reproduction.

  • Retrieved from "https://en.wikipedia.org/w/index.php?title=Chelates_in_animal_nutrition&oldid=1200993265"
     



    Last edited on 30 January 2024, at 18:07  





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