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ETFELA





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ETFELA (N-ethyl-N-(2,2,2-trifluoroethyl)lysergamide) is an analogoflysergic acid diethylamide (LSD) first synthesised by Jason C. Parrish as part of the research team led by David E. Nichols. In studies in vitro, it was found to be slightly more potent than LSD itself.[1][2]

ETFELA
Clinical data
Other namesLA-CH2CF3
Identifiers

  • (6aR,9R)-N-Ethyl-7-methyl-N-(2,2,2-trifluoroethyl)-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide

CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H22F3N3O
Molar mass377.411 g·mol−1
3D model (JSmol)

  • CCN(C(=O)[C@H]1CN(C)[C@H]2C(=C1)c1cccc3c1c(C2)c[nH]3)CC(F)(F)F

  • InChI=1S/C20H22F3N3O/c1-3-26(11-20(21,22)23)19(27)13-7-15-14-5-4-6-16-18(14)12(9-24-16)8-17(15)25(2)10-13/h4-7,9,13,17,24H,3,8,10-11H2,1-2H3/t13-,17-/m1/s1

  • Key:VAHPXTJQSWECIC-CXAGYDPISA-N

See also

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References

edit
  1. ^ Nichols DE (2012). "Structure-activity relationships of serotonin 5-HT2A agonists". Wiley Interdisciplinary Reviews: Membrane Transport and Signaling. 1 (5): 559–579. doi:10.1002/wmts.42.
  • ^ Nichols DE (2017). "Chemistry and Structure-Activity Relationships of Psychedelics". Current Topics in Behavioral Neurosciences. 36: 1–43. doi:10.1007/7854_2017_475. ISBN 978-3-662-55878-2. PMID 28401524. S2CID 4396184.


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    Last edited on 4 February 2024, at 22:00  





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    ●This page was last edited on 4 February 2024, at 22:00 (UTC).
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