Home  

Random  

Nearby  



Log in  



Settings  



Donate  



About Wikipedia  

Disclaimers  



Wikipedia





Galangin





Article  

Talk  



Language  

Watch  

Edit  





Galangin is a flavonol, a type of flavonoid.

Galangin
Skeletal formula of galangin
Ball-and-stick model of the galangin molecule
Names
IUPAC name

3,5,7-Trihydroxyflavone

Systematic IUPAC name

3,5,7-Trihydroxy-2-phenyl-4H-1-benzopyran-4-one

Other names

Norizalpinin
3,5,7-triOH-Flavone

Identifiers

CAS Number

3D model (JSmol)

ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.008.147 Edit this at Wikidata

IUPHAR/BPS

KEGG

PubChem CID

UNII

CompTox Dashboard (EPA)

  • InChI=1S/C15H10O5/c16-9-6-10(17)12-11(7-9)20-15(14(19)13(12)18)8-4-2-1-3-5-8/h1-7,16-17,19H checkY

    Key: VCCRNZQBSJXYJD-UHFFFAOYSA-N checkY

  • InChI=1/C15H10O5/c16-9-6-10(17)12-11(7-9)20-15(14(19)13(12)18)8-4-2-1-3-5-8/h1-7,16-17,19H

    Key: VCCRNZQBSJXYJD-UHFFFAOYAC

  • O=C1c3c(O/C(=C1/O)c2ccccc2)cc(O)cc3O

Properties

Chemical formula

C15H10O5
Molar mass 270.240 g·mol−1
Density 1.579 g/mL
Melting point 214 to 215 °C (417 to 419 °F; 487 to 488 K)

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

checkY verify (what is checkY☒N ?)

Infobox references

Occurrence

edit

Galangin is found in high concentrations in plants like Alpinia officinarum (lesser galangal)[1] and Helichrysum aureonitens.[2] It is also found in the rhizomeofAlpinia galanga[3] and in propolis.[4]

Biological activities

edit

Galangin has been shown to have in vitro antibacterial[5][6] and antiviral activity.[7] It also inhibits the growth of breast tumor cells in vitro.[8][9]

References

edit
  1. ^ Ciolino, H. P.; Yeh, G. C. (1999). "The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor". British Journal of Cancer. 79 (9/10): 1340–1346. doi:10.1038/sj.bjc.6690216. PMC 2362711. PMID 10188874.
  • ^ Afolayan AJ, Meyer JJ (1997). "The antimicrobial activity of 3,5,7-trihydroxyflavone isolated from the shoots of Helichrysum aureonitens". Journal of Ethnopharmacology. 57 (3): 177–181. doi:10.1016/s0378-8741(97)00065-2. PMID 9292410.
  • ^ Kaur, A.; Singh, R.; Dey, C. S.; Sharma, S. S.; Bhutani, K. K.; Singh, I. P. (2010). "Antileishmanial phenylpropanoids from Alpinia galanga (Linn.) Willd" (PDF). Indian Journal of Experimental Biology. 48 (3): 314–317. PMID 21046987.
  • ^ Tosi, E; Re, E; Ortega, M; Cazzoli, A (2007). "Food preservative based on propolis: Bacteriostatic activity of propolis polyphenols and flavonoids upon Escherichia coli". Food Chemistry. 104 (3): 1025–1029. doi:10.1016/j.foodchem.2007.01.011.
  • ^ Cushnie TP, Lamb AJ (2006). "Assessment of the antibacterial activity of galangin against 4-quinolone resistant strains of Staphylococcus aureus". Phytomedicine. 13 (3): 187–191. doi:10.1016/j.phymed.2004.07.003. PMID 16428027.
  • ^ Cushnie TP, Lamb AJ (2005). "Detection of galangin-induced cytoplasmic membrane damage in Staphylococcus aureus by measuring potassium loss". Journal of Ethnopharmacology. 101 (1–3): 243–248. doi:10.1016/j.jep.2005.04.014. PMID 15985350.
  • ^ Afolayan AJ, Meyer JJ, Taylor MB, Erasmus D (1997). "Antiviral activity of galangin isolated from the aerial parts of Helichrysum aureonitens". Journal of Ethnopharmacology. 56 (2): 165–169. doi:10.1016/s0378-8741(97)01514-6. PMID 917497.
  • ^ So, F. V.; Guthrie, N.; Chambers, A. F.; Moussa, M.; Carroll, K. K. (1996). "Inhibition of human breast cancer cell proliferation and delay of mammary tumorigenesis by flavonoids and citrus juices". Nutrition and Cancer. 26 (2): 167–181. doi:10.1080/01635589609514473. PMID 8875554.
  • ^ So, F.; Guthrie, N.; Chambers, A. F.; Carroll, K. K. (1997). "Inhibition of proliferation of estrogen receptor-positive MCF-7 human breast cancer cells by flavonoids in the presence and absence of excess estrogen". Cancer Letters. 112 (2): 127–133. doi:10.1016/S0304-3835(96)04557-0. PMID 9066718.
  • edit

    Retrieved from "https://en.wikipedia.org/w/index.php?title=Galangin&oldid=1162495597"
     



    Last edited on 29 June 2023, at 14:42  





    Languages

     


    تۆرکجه
    Español
    فارسی
    Français
    Italiano

    Polski
    Română
    Русский
    Српски / srpski
    Srpskohrvatski / српскохрватски

     

    Wikipedia


    This page was last edited on 29 June 2023, at 14:42 (UTC).

    Content is available under CC BY-SA 4.0 unless otherwise noted.



    Privacy policy

    About Wikipedia

    Disclaimers

    Contact Wikipedia

    Code of Conduct

    Developers

    Statistics

    Cookie statement

    Terms of Use

    Desktop