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He is known for the Nierenstein reaction , an organic reaction describing the conversion of an acid chloride into an haloketone with diazomethane.
In 1912, Polish biochemist Casimir Funk isolated a complex of micronutrients and proposed the complex be named "vitamine " (a portmanteau of "vital amine"), a name reportedly suggested by friend Max Nierenstein.[1 ] [2 ]
He also studied natural phenols and tannins [3 ] found in different plant species. He showed in 1945 that luteic acid , a molecule present in the myrobalanitannin , a tannin found in the fruit of Terminalia chebula , is an intermediary compound in the synthesis of ellagic acid .[4 ] Working with Arthur George Perkin , he prepared ellagic acid from algarobilla and certain other fruits in 1905.[5 ] He suggested its formation from galloyl -glycine by Penicillium in 1915.[6 ] Tannase is an enzyme that Niederstein used to produce m-digallic acid from gallotannins .[7 ] He proved the presence of catechin in cocoa beans in 1931.[8 ]
He also worked on milk and caseinogen .[9 ] He reviewed the discovery of lactose in 1936.[10 ]
Works
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Nierenstein, Moses Max (1904). Synthese des 2-Oxyflavonols .
Moore, Benjamin; Nierenstein, Maximilian; Todd, John Lancelot; Liverpool School of Tropical Medicine (1908). Concerning the Treatment of Experimental Trypanosomiasis .
Nierenstein, Maximilian (1910). Chemie der Gerbstoffe .
Nierenstein, M (1912). Organische Arsenverbindungen und ihre chemotherapeutische Bedeutung .
Nierenstein, M (1932). Incunabula of tannin chemistry: A collection of some early papers on the chemistry of the tannins reproduced in facsimile and published with annotations .
Nierenstein, Maximilian; Skene, Macgregor (1934). The Natural Organic Tannins: History, Chemistry, Distribution .
References
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^ Funk, C.; Dubin, H. E. (1922). The Vitamines . Baltimore: Williams and Wilkins Company. The Vitamines.
^ Drabble, E.; Nierenstein, M. (1907). "On the Rôle of Phenols, Tannic Acids, and Oxybenzoic Acids in Cork Formation" . Biochemical Journal . 2 (3 ): 96–102.1. doi :10.1042/bj0020096 . PMC 1276196 . PMID 16742048 .
^ Nierenstein, M.; Potter, J. (1945). "The distribution of myrobalanitannin" . The Biochemical Journal . 39 (5 ): 390–392. doi :10.1042/bj0390390 . PMC 1258254 . PMID 16747927 .
^ Perkin, A. G.; Nierenstein, M. (1905). "CXLI.—Some oxidation products of the hydroxybenzoic acids and the constitution of ellagic acid. Part I" . Journal of the Chemical Society, Transactions . 87 : 1412–1430. doi :10.1039/CT9058701412 .
^ Nierenstein, M. (1915). "The Formation of Ellagic Acid from Galloyl-Glycine by Penicillium " . The Biochemical Journal . 9 (2 ): 240–244. doi :10.1042/bj0090240 . PMC 1258574 . PMID 16742368 .
^ Nierenstein, M. (1932). "A biological synthesis of m-digallic acid" . The Biochemical Journal . 26 (4 ): 1093–1094. doi :10.1042/bj0261093 . PMC 1261008 . PMID 16744910 .
^ Adam, W. B.; Hardy, F.; Nierenstein, M. (1931). "The Catechin of the Cacao Bean". Journal of the American Chemical Society . 53 (2 ): 727–728. doi :10.1021/ja01353a041 .
^ Geake, A.; Nierenstein, M. (1914). "The Action of Diazomethane on Caseinogen: Preliminary Communication" . The Biochemical Journal . 8 (4 ): 287–292. doi :10.1042/bj0080287 . PMC 1276579 . PMID 16742318 .
^ Nierenstein, M. (February 1936). "The Discovery of Lactic Sugar". Isis . 24 (2 ): 367–369. doi :10.1086/347034 . JSTOR 225293 . S2CID 143519796 .
External links
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R e t r i e v e d f r o m " https://en.wikipedia.org/w/index.php?title=Maximilian_Nierenstein&oldid=1198965853 "
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