Nexafed is a formulation of pseudoephedrine developed by Acura Pharmaceuticals used to deter the use of the pseudoephedrine contained in the product for illicit methamphetamine synthesis.[1] Nexafed uses a polymer matrix that forms a thick gel when hydrated, preventing the extraction of pseudoephedrine.[2] Nexafed is the only meth-resistant formulation of pseudoephedrine that shows therapeutic equivalence to Sudafed.[3]
It is sold at various pharmacies in the US, including Fruth Pharmacy[4][5] and Kroger, particularly in communities where illicit methamphetamine production is an issue.[citation needed]
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