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Pentylone





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"NRG-3" redirects here. For the protein growth factor, see Neuregulin 3.

Pentylone (β-Keto-Methyl​benzo​dioxolyl​pentanamine, βk-Methyl-K, βk-MBDP, methyl​enedioxy​pentedrone, or 1‐(3,4‐methylenedioxyphenyl)‐2‐(methylamino)pentan‐1‐one[2]) is a stimulant developed in the 1960s.[3] It is a substituted cathinone (a type of substituted phenethylamine). It has been identified in some samples of powders sold as "NRG-1", along with varying blends of other cathinone derivatives including flephedrone, MDPBP, MDPV and 4-MePPP. It was also found in combination with 4-MePPP being sold as "NRG-3".[2] Reports indicate side effects include feelings of paranoia, agitation and inability to sleep, with effects lasting for several days at high doses.[4]

Pentylone
Clinical data
ATC code
  • none
Legal status
Legal status
  • DE: Anlage I (Authorized scientific use only)
  • UK: Class B
  • US: Schedule I
  • Illegal in Sweden and Finland
    • Identifiers

    • (±)-1-(1,3-benzodioxol-5-yl)-2-(methylamino)pentan-1-one

    CAS Number
    PubChem CID
    ChemSpider
    UNII
    CompTox Dashboard (EPA)
    Chemical and physical data
    FormulaC13H17NO3
    Molar mass235.283 g·mol−1
    3D model (JSmol)

    • c2cc1OCOc1cc2C(=O)C(NC)CCC

    • InChI=1S/C13H17NO3/c1-3-4-10(14-2)13(15)9-5-6-11-12(7-9)17-8-16-11/h5-7,10,14H,3-4,8H2,1-2H3 ☒N

    • Key:DFMLULIEUUXXSA-UHFFFAOYSA-N ☒N

     ☒NcheckY (what is this?)  (verify)

    Pharmacology

    edit

    Pentylone acts as a serotonin-norepinephrine-dopamine reuptake inhibitor and a serotonin releasing agent.[5]

    Legality

    edit

    Pentylone is banned in Canada, Germany, Sweden, the United States and in the UK.[6][7]

    See also

    edit

    References

    edit
    1. ^ Anvisa (2023-07-24). "RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-07-25). Archived from the original on 2023-08-27. Retrieved 2023-08-27.
  • ^ a b Brandt SD, Freeman S, Sumnall HR, Measham F, Cole J (September 2011). "Analysis of NRG 'legal highs' in the UK: identification and formation of novel cathinones". Drug Testing and Analysis. 3 (9): 569–575. doi:10.1002/dta.204. PMID 21960541.
  • ^ GB 1085135, "Substituted phenyl-α-amino ketones.", issued 1969 
  • ^ Bish J (4 August 2017). "Watch Out for Pentylone, the Horrible New MDMA Additive". Vice.
  • ^ Simmler LD, Rickli A, Hoener MC, Liechti ME (April 2014). "Monoamine transporter and receptor interaction profiles of a new series of designer cathinones". Neuropharmacology. 79: 152–160. doi:10.1016/j.neuropharm.2013.11.008. PMID 24275046. S2CID 25259854.
  • ^ "Cannabinoider föreslås bli klassade som hälsofarlig vara" [Cannabinoids are proposed to be classified as a health hazard]. Folkhalsomyndigheten [Public Health Agency of Sweden] (in Swedish). Archived from the original on 25 March 2015. Retrieved 29 June 2015.
  • ^ "Schedules of Controlled Substances: Temporary Placement of 10 Synthetic Cathinones Into Schedule I". Drug Enforcement Administration. U.S. Federal Register. 7 March 2014.
    •  

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    • Retrieved from "https://en.wikipedia.org/w/index.php?title=Pentylone&oldid=1181505223"
      



    Last edited on 23 October 2023, at 13:06  





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