Phorate is an organophosphate used as an insecticide and acaricide.
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| Names | |
|---|---|
| Preferred IUPAC name
O,O-Diethyl S-[(ethylsulfanyl)methyl] phosphorodithioate | |
| Other names
Thimet (trademark) | |
| Identifiers | |
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3D model (JSmol) |
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| ChEBI | |
| ChEMBL | |
| ChemSpider |
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| ECHA InfoCard | 100.005.503 
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PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C7H17O2PS3 | |
| Molar mass | 260.36 g·mol−1 |
| Appearance | Colorless liquid |
| Odor | Skunk-like[1] |
| Density | 1.16 g/mL |
| Melting point | −43 °C; −45 °F; 230 K[1] |
| Boiling point | 118-120°C (2.0 mm Hg)[2] |
| 0.005% (20°C)[1] | |
| Vapor pressure | 0.0008 mmHg (20°C)[1] |
| Hazards | |
| Flash point | 160 °C; 320 °F; 433 K (open cup)[1] |
| NIOSH (US health exposure limits): | |
PEL (Permissible) |
none[1] |
REL (Recommended) |
TWA 0.05 mg/m3 ST 0.2 mg/m3 [skin][1] |
IDLH (Immediate danger) |
N.D.[1] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
At normal conditions, it is a pale yellow mobile liquid poorly solubleinwater but readily soluble in organic solvents. It is relatively stable and hydrolyses only at very acidicorbasic conditions. It is very toxic both for target organisms and for mammals including humans. It inhibits acetylcholinesterase and butyrylcholinesterase.[3]
Phorate is most commonly applied in granular form. It is non-biocumulative and has no residual action. But some metabolites may persist in soil. It also damages some seeds.[3]
Phorate (Thimate) is absorbed readily through all ways. Its toxicity is high. Oral LD50torats is 1.1 – 3.2 mg/kg, to mice 3.5 – 6.5 mg/kg (technical phorate). Similar values has been found out to birds.[3]
