Phosalone is an organophosphate chemical commonly used as an insecticide and acaricide. It is developed by Rhône-Poulenc in France but EU eliminated it from pesticide registration in December 2006.
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| Names | |
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| Preferred IUPAC name
S-[(6-Chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl phosphorodithioate | |
| Other names
Zolone | |
| Identifiers | |
3D model (JSmol) |
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| ChEBI | |
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| ECHA InfoCard | 100.017.270 
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| KEGG |
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PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C12H15ClNO4PS2 | |
| Molar mass | 367.80 g·mol−1 |
| Appearance | Colorless crystalline |
| Odor | garlic |
| Density | 1.39 g cm−3 |
| Melting point | 47.5 to 48 °C (117.5 to 118.4 °F; 320.6 to 321.1 K) |
| 3.05 mg/L | |
| Solubility | many organic solvents |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
The median lethal dose of oral exposure in rat is 85 mg/kg and that of dermal is 390 mg/kg.[1]。It is a weak acetylcholinesterase inhibitor.[2] It is taken by not only oral and inhalation but skin and it causes toxic symptoms peculiar to organophosphorus compounds such as miosis, hypersalivation, hyperhidrosis, chest pressure, pulmonary edema and fecal incontinence.[3] It is flammable and decomposes to toxic gases such as phosphorus oxides, sulfur oxides and nitrogen oxides.[2] It is harmful especially to water creatures.
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