Rauvolfia serpentina, the Indian snakeroot, devil pepper, or serpentine wood,[4] is a species of flower in the milkweed family Apocynaceae.[5] It is native to the Indian subcontinent and East Asia (from IndiatoIndonesia).[6][7]
| Rauvolfia serpentina | |
|---|---|
| |
Scientific classification 
| |
| Kingdom: | Plantae |
| Clade: | Tracheophytes |
| Clade: | Angiosperms |
| Clade: | Eudicots |
| Clade: | Asterids |
| Order: | Gentianales |
| Family: | Apocynaceae |
| Genus: | Rauvolfia |
| Species: |
R. serpentina
|
| Binomial name | |
| Rauvolfia serpentina | |
| Synonyms[3] | |
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Rauvolfia is a perennial undershrub widely distributed in India in the sub-Himalayan regions up to 1,000 metres (3,300 ft).
Rauvolfia serpentina contains dozens of alkaloids of the indole alkaloid family, including ajmaline, ajmalicine, reserpine, and serpentine, among others.[5][8]
A 2016 review found that reserpine reduced systolic blood pressure (SBP) by about 8 mmHg compared to placebo, and may be as effective at reducing SBP as other front-line hypertensive drugs, although more research is needed to determine a dose-specific safety profile.[9]
R. serpentina may cause adverse effects by interacting with various prescription drugs[10] or via interference with mechanisms of mental depressionorpeptic ulcer.[10] The reserpine in R. serpentina is associated with diverse adverse effects, including vomiting, diarrhea, dizziness, headache, anxiety, or hypersensitivity reactions.[5]
