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Sodium astatide





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Sodium astatide is a binary inorganic compound of sodium and astatine with the chemical formula NaAt.[2][3]

Sodium astatide
Names
Preferred IUPAC name

Sodium astatide

Identifiers

3D model (JSmol)

  • [Na+].[At-]

Properties

Chemical formula

NaAt
Thermochemistry

Std enthalpy of
formation
fH298)

−257 kJ/mol (estimated)[1]
Related compounds

Related compounds

Magnesium astatide

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Infobox references

Synthesis

edit

Sodium astatide solution has been prepared by distilling astatine from the bismuth alpha-ray target where it was prepared, dissolving in sodium bicarbonate solution, and reducing At+ and At3+ ions with ascorbic acid.[4]

Uses

edit

Sodium astatide has been proposed for use in radiation therapy to replace 131I.[5][4]

References

edit
  1. ^ Burgers, Peter C.; Zeneyedpour, Lona; Luider, Theo M.; Holmes, John L. (2024). "Estimation of thermodynamic and physicochemical properties of the alkali astatides: On the bond strength of molecular astatine (At 2 ) and the hydration enthalpy of astatide (At − )". Journal of Mass Spectrometry. 59 (4). doi:10.1002/jms.5010. ISSN 1076-5174.
  • ^ Watabe, Tadashi; Hosono, Makoto; Kinuya, Seigo; Yamada, Takahiro; Yanagida, Sachiko; Namba, Masao; Nakamura, Yoshihide (July 2021). "Manual on the proper use of sodium astatide ([211At]NaAt) injections in clinical trials for targeted alpha therapy (1st edition)". Annals of Nuclear Medicine. 35 (7): 753–766. doi:10.1007/s12149-021-01619-2. ISSN 1864-6433. PMC 8197710. PMID 33978932.
  • ^ Ball, Philip (17 March 2020). "An affinity for astatine". Chemistry World. Retrieved 16 June 2023.
  • ^ a b Y. Shirakami. "Preparation of [211At]-labeled sodium astatide (NaAt) by reducing with ascorbic acid for the treatment of thyroid cancer" (PDF). RIKEN Accel. Prog. Rep. 53: 171. Retrieved 16 June 2023.
  • ^ "Breakthrough alpha-ray treatment of cancer without external radiation". EurekAlert!. Retrieved 16 June 2023.

  • Retrieved from "https://en.wikipedia.org/w/index.php?title=Sodium_astatide&oldid=1231952685"
     



    Last edited on 1 July 2024, at 04:26  





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    This page was last edited on 1 July 2024, at 04:26 (UTC).

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