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This review blames hepcidin for everything. JFW | T@lk 08:00, 8 December 2005 (UTC)Reply
Words like "Recently" and "soon after" are not as useful to the reader as actual dates. —Preceding unsigned comment added by 61.214.155.14 (talk) 08:31, 26 November 2007 (UTC)Reply
When there's an excess of hepcidin (you have enough iron in your system) and an excess of iron passing the enterocytes in the intestine, how do enterocytes prevent too much iron entering their cytoplasma? — Preceding unsigned comment added by 80.218.105.42 (talk) 08:00, 4 June 2014 (UTC)Reply
They don't. They just save it up and take it with them when they die and are shed.
I know this straddles several areas but there is a fair amount of data on the gene and protein and less on the physiology from what I can tell so I think that the WP:MCBMOS style guide is must productive way to structure article.
My interest is from reading about erythropheresis in cancer but obviously iron homeostasis encompasses a lot more than that.
The sentence below is at best unclear. IMHO it should read "When the hepcidin level is abnormally low such as in hemochromatosis, iron overload occurs due to increased ferroportin mediated iron efflux from enterocytes".
When the hepcidin level is abnormally low such as in hemochromatosis, iron overload occurs due to decreased ferroportin mediated iron efflux.
This article was the subject of a Wiki Education Foundation-supported course assignment, between 30 August 2022 and 16 December 2022. Further details are available on the course page. Student editor(s): Kf7tgy22 (article contribs). Peer reviewers: ScholarJay, Koberg27.
— Assignment last updated by ETstem (talk) 16:31, 13 October 2022 (UTC)Reply
Traditional therapy for iron deficiency anemia includes taking iron pills, daily. But exogenous iron induces hepcidin, which inhibits iron uptake. It's better to take exogenous iron every OTHER day, since hepcidin wears off after 48 hours.Richard8081 (talk) 02:24, 19 April 2023 (UTC)Reply
