Compound | hPR-A | hPR-B | rbPR | rbGR | rbER | |||
---|---|---|---|---|---|---|---|---|
Progesterone | 100 | 100 | 100 | <1 | <1 | |||
17α-Hydroxyprogesterone | 1 | 1 | 3 | 1 | <1 | |||
Hydroxyprogesterone caproate | 26 | 30 | 28 | 4 | <1 | |||
Hydroxyprogesterone acetate | 38 | 46 | 115 | 3 | ? | |||
Notes: Values are percentages (%). Reference ligands (100%) were progesterone for the PRTooltip progesterone receptor, dexamethasone for the GRTooltip glucocorticoid receptor, and estradiol for the ERTooltip estrogen receptor. Sources: [1][2] |