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Trioxane

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Trioxane refers to any of three isomeric organic compounds composed of a six-membered ring with three carbon atoms and three oxygen atoms, having the molecular formulaC₃H₆O₃.

Trioxane isomers:1,2,3-trioxane (left), 1,2,4-trioxane (middle), and 1,3,5-trioxane (right)

Isomers

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The three isomers are:

1,2,3-trioxane, a hypothetical compound that is the parent structure of the molozonides^[1]
1,2,4-trioxane, a hypothetical compound whose skeleton occurs as a structural element of some antimalarial agents (artemisinin and similar drugs)^[2]
1,3,5-trioxane, a trimer of formaldehyde used as fuel and in plastics manufacturing, and also as a solid fuel tablet when combined with hexamine

References

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^ Lay, Tsan H.; Yamada, Takahiro; Tsai, Po-Lun; Bozzelli, Joseph W. (1997). "Thermodynamic Parameters and Group Additivity Ring Corrections for Three- to Six-Membered Oxygen Heterocyclic Hydrocarbons". Journal of Physical Chemistry A. 101 (13): 2471–2477. Bibcode:1997JPCA..101.2471L. doi:10.1021/jp9629497.

^ Gary H. Posner, Mikhail Krasavin, Michael McCutchen, Poonsakdi Ploypradith, John P. Maxwell, Jeffrey S. Elias, Michael H. Parker (2001). "New antimalarial trioxanes and endoperoxides". Antimalarial Chemotherapy: 255–263.{{cite journal}}: CS1 maint: multiple names: authors list (link)

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Retrieved from "https://en.wikipedia.org/w/index.php?title=Trioxane&oldid=1227611493" Last edited on 6 June 2024, at 19:54

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