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m Reverted 1 edit by 66.87.150.246 identified as test/vandalism using STiki
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Removed parameters. | Use this bot. Report bugs. | Suggested by AManWithNoPlan | Category:CS1 maint: url-status | #UCB_Category 90/1592
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| verifiedrevid = 442524832 |
| verifiedrevid = 442524832 |
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| Name = Isopropyl myristate |
| Name = Isopropyl myristate |
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| Reference = <ref>{{Cite web |title=SAFETY DATA SHEET |url=https://www.fishersci.com/store/msds?partNumber=AC412851000&countryCode=US&language=en |access-date=2024-05-05 |website=Fisher Scientific |publication-date=2009-09-22}}</ref> |
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| Reference = <ref>[http://www.physchem.ox.ac.uk/MSDS/IS/isopropyl_myristate.html MSDS for isopropyl myristate]</ref> |
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| ImageFile = Isopropyl myristate.png |
| ImageFile = Isopropyl myristate.png |
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| ImageSize = 200px |
| ImageSize = 200px |
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| ImageName = Isopropyl myristate |
| ImageName = Isopropyl myristate |
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| |
| PIN = Propan-2-yl tetradecanoate |
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| OtherNames = Tetradecanoic acid, 1-methylethyl ester<br />Myristic acid isopropyl ester |
| OtherNames = Tetradecanoic acid, 1-methylethyl ester<br />Myristic acid isopropyl ester |
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|Section1={{Chembox Identifiers |
|Section1={{Chembox Identifiers |
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| Line 14: | Line 14: | ||
| CASNo_Ref = {{cascite|correct|CAS}} |
| CASNo_Ref = {{cascite|correct|CAS}} |
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| CASNo = 110-27-0 |
| CASNo = 110-27-0 |
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| ChEMBL = 207602 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = 0RE8K4LNJS |
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| EINECS = 203-751-4 |
| EINECS = 203-751-4 |
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| RTECS = XB8600000 |
| RTECS = XB8600000 |
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| PubChem = 8042 |
| PubChem = 8042 |
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| ChemSpiderID_Ref = {{chemspidercite| |
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 7751 |
| ChemSpiderID = 7751 |
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| InChI = 1/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3 |
| InChI = 1/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3 |
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| MeSHName = C008205 |
| MeSHName = C008205 |
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| ChEBI = |
| ChEBI = |
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| KEGG_Ref = {{keggcite| |
| KEGG_Ref = {{keggcite|correct|kegg}} |
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| KEGG = D02296 |
| KEGG = D02296 |
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}} |
}} |
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| C=17 | H=34 | O=2 |
| C=17 | H=34 | O=2 |
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| Appearance = |
| Appearance = |
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| Density = 0.85 g/cm |
| Density = 0.85 g/cm<sup>3</sup> |
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| Solubility = |
| Solubility = |
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| MeltingPt = |
| MeltingPt = |
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| NFPA-R = 0 |
| NFPA-R = 0 |
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| FlashPt = |
| FlashPt = |
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| RPhrases = {{R38}} |
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| SPhrases = {{S24/25}} |
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}} |
}} |
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|Section8={{Chembox Related |
|Section8={{Chembox Related |
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| Line 65: | Line 66: | ||
}} |
}} |
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'''Isopropyl myristate''' is the [[ester]] of [[ |
'''Isopropyl myristate''' (IPM) is the [[ester]] of [[isopropyl alcohol]] and [[myristic acid]]. |
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==Uses== |
==Uses== |
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Isopropyl myristate is used in cosmetic and topical |
Isopropyl myristate is a polar [[Moisturizer|emollient]] and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired. It is also used as a treatment for [[pediculosis|head lice]].<ref>{{Cite web |title=Anti-Lice Treatments |url=http://www.lice.ca/treatment/anti_lice_insecticide.html |access-date=2024-05-05 |website=www.lice.ca}}</ref> It is also in flea and tick killing products for pets. |
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| ⚫ | It is used to remove bacteria from the oral cavity as the [[non-aqueous]] component of the two-phase [[mouthwash]] product "[[Dentyl pH]]". |
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It is used as a solvent in perfume materials. |
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| ⚫ | Isopropyl myristate is also used as a solvent in perfume materials, and in the removal process of [[prosthetic make-up]]. |
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| ⚫ |
It is the [[non-aqueous]] component of the two-phase mouthwash |
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[[Hydrolysis]] of the ester from isopropyl myristate can liberate the acid and the alcohol. The acid is theorized to be responsible for decreasing of the pH value of formulations.<ref>Wen, Z.; Fang, L. and He, Z. (2009). Effect of chemical enhancers on percutaneous absorption of daphnetin in isopropyl myristate vehicle across rat skin in vitro. Drug Deliv, 16: 214-223</ref><ref>Engelbrecht, T.; Demé, B.; Dobner, B. and Neubert, R. (2012). Study of the influence of the penetration enhancer isopropyl myristate on the nanostructure of stratum corneum lipid model membranes using neutron diffraction and deuterium labelling. Skin Pharmacol Physiol, 25:200-7</ref> |
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| ⚫ |
|
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It is also used in flea and tick products for pets. |
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==References== |
==References== |
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==External links== |
==External links== |
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* {{ |
* {{CPID|id=94}} |
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{{Cosmetics}} |
{{Cosmetics}} |
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| Line 88: | Line 87: | ||
[[Category:Carboxylate esters]] |
[[Category:Carboxylate esters]] |
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[[Category:Cosmetics chemicals]] |
[[Category:Cosmetics chemicals]] |
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[[Category:Isopropyl esters]] |
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| |
| Names | |
|---|---|
| Preferred IUPAC name
Propan-2-yl tetradecanoate | |
| Other names
Tetradecanoic acid, 1-methylethyl ester | |
| Identifiers | |
| |
3D model (JSmol) |
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| ChEMBL | |
| ChemSpider |
|
| ECHA InfoCard | 100.003.412 
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| EC Number |
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| KEGG |
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| MeSH | C008205 |
PubChem CID |
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| RTECS number |
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| UNII | |
CompTox Dashboard (EPA) |
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| |
| |
| Properties | |
| C17H34O2 | |
| Molar mass | 270.457 g·mol−1 |
| Density | 0.85 g/cm3 |
| Boiling point | 167 °C (333 °F; 440 K) at 9 mmHg |
| Hazards | |
| NFPA 704 (fire diamond) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Isopropyl myristate (IPM) is the esterofisopropyl alcohol and myristic acid.
Isopropyl myristate is a polar emollient and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired. It is also used as a treatment for head lice.[2] It is also in flea and tick killing products for pets.
It is used to remove bacteria from the oral cavity as the non-aqueous component of the two-phase mouthwash product "Dentyl pH".
Isopropyl myristate is also used as a solvent in perfume materials, and in the removal process of prosthetic make-up.
Hydrolysis of the ester from isopropyl myristate can liberate the acid and the alcohol. The acid is theorized to be responsible for decreasing of the pH value of formulations.[3][4]
