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{{Short description|Classification of membrane proteins including ion channels}} |
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The '''Transporter Classification Database''' (or '''TCDB''') is an [[International Union of Biochemistry and Molecular Biology]] (IUBMB)-approved classification system for [[membrane transport protein]]s, including [[ion channel]]s.<ref>{{cite journal|last1=Saier|first1=Milton H.|last2=Reddy|first2=Vamsee S.|last3=Tamang|first3=Dorjee G.|last4=Västermark|first4=Åke|title=The Transporter Classification Database|journal=Nucleic Acids Research|date=January 2014|volume=42|issue=D1|pages=D251–D258|doi=10.1093/nar/gkt1097|url= |
The '''Transporter Classification Database''' (or '''TCDB''') is an [[International Union of Biochemistry and Molecular Biology]] (IUBMB)-approved classification system for [[membrane transport protein]]s, including [[ion channel]]s.<ref>{{cite journal|last1=Saier|first1=Milton H.|last2=Reddy|first2=Vamsee S.|last3=Tamang|first3=Dorjee G.|last4=Västermark|first4=Åke|title=The Transporter Classification Database|journal=Nucleic Acids Research|date=January 2014|volume=42|issue=D1|pages=D251–D258|doi=10.1093/nar/gkt1097|pmid=24225317|url= |pmc=3964967}}</ref><ref>{{cite journal|last1=Saier|first1=M. H.|last2=Yen|first2=M. R.|last3=Noto|first3=K.|last4=Tamang|first4=D. G.|last5=Elkan|first5=C.|title=The Transporter Classification Database: recent advances|journal=Nucleic Acids Research|date=1 January 2009|volume=37|issue=Database|pages=D274–D278|doi=10.1093/nar/gkn862|url= |pmid=19022853|pmc=2686586}}</ref><ref>{{cite journal|last1=Saier|first1=M. H.|last2=Tran|first2=C. V.|last3=Barabote|first3=R. D.|title=TCDB: the Transporter Classification Database for membrane transport protein analyses and information|journal=Nucleic Acids Research|date=1 January 2006|volume=34|issue=90001|pages=D181–D186|doi=10.1093/nar/gkj001|url= |pmid=16381841|pmc=1334385}}</ref> |
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==Classification== |
==Classification== |
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====1.A α-type channels==== |
====1.A α-type channels==== |
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* 1.A.1 [[Voltage-gated ion channel|Voltage-gated ion channel superfamily]] |
* 1.A.1 [[Voltage-gated ion channel|Voltage-gated ion channel superfamily]] |
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* 1.A.2 |
* 1.A.2 [[inward-rectifier K+ channel|Inward-rectifier K<sup>+</sup> channel family]] |
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* 1.A.3 [[Ryanodine-inositol-1,4,5-trisphosphate receptor Ca2+ channel|Ryanodine-inositol-1,4,5-trisphosphate receptor Ca<sup>2+</sup> channel family]] |
* 1.A.3 [[Ryanodine-inositol-1,4,5-trisphosphate receptor Ca2+ channel|Ryanodine-inositol-1,4,5-trisphosphate receptor Ca<sup>2+</sup> channel family]] |
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* 1.A.4 [[Transient receptor potential Ca2+ channel|Transient receptor potential Ca<sup>2+</sup> channel family]] |
* 1.A.4 [[Transient receptor potential Ca2+ channel|Transient receptor potential Ca<sup>2+</sup> channel family]] |
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* 1.A.34 [[Bacillus gap junction-like channel-forming complex family|''Bacillus'' gap junction-like channel-forming complex family]] |
* 1.A.34 [[Bacillus gap junction-like channel-forming complex family|''Bacillus'' gap junction-like channel-forming complex family]] |
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* 1.A.35 [[CorA metal ion transporter|CorA metal ion transporter family]] |
* 1.A.35 [[CorA metal ion transporter|CorA metal ion transporter family]] |
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* 1.A.36 [[ |
* 1.A.36 [[Chloride channel#CLIC family|Intracellular chloride channel family]] |
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* 1.A.37 [[The CD20 Ca2+ channel family|CD20 Ca<sup>2+</sup> channel family]] |
* 1.A.37 [[The CD20 Ca2+ channel family|CD20 Ca<sup>2+</sup> channel family]] |
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* 1.A.38 [[The Golgi pH regulator family|Golgi pH regulator family]] |
* 1.A.38 [[The Golgi pH regulator family|Golgi pH regulator family]] |
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* 1.A.39 [[Type C Influenza Virus CM2 Channel (CM2-C) Family|Type C influenza virus CM2 channel family]] |
* 1.A.39 [[Type C Influenza Virus CM2 Channel (CM2-C) Family|Type C influenza virus CM2 channel family]] |
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* 1.A.40 [[ |
* 1.A.40 [[Vpu protein|Human immunodeficiency virus type I Vpu channel family]] |
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* 1.A.41 [[Avian reovirus p10 Vvroporin family]] |
* 1.A.41 [[Avian reovirus p10 Vvroporin family]] |
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* 1.A.42 [[HIV viral protein R family]] |
* 1.A.42 [[HIV viral protein R family]] |
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* 1.A.49 [[Human coronavirus ns12.9 viroporin family]] |
* 1.A.49 [[Human coronavirus ns12.9 viroporin family]] |
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* 1.A.50 [[phospholamban|Phospholamban (Ca<sup>2+</sup>-channel and Ca<sup>2+</sup>-ATPase regulator) family]] |
* 1.A.50 [[phospholamban|Phospholamban (Ca<sup>2+</sup>-channel and Ca<sup>2+</sup>-ATPase regulator) family]] |
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*1.A.51 The Voltage-gated Proton Channel (VPC) Family |
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*1.A.52 The Ca<sup>2+</sup> Release-activated Ca<sup>2+</sup> (CRAC) Channel (CRAC-C) Family |
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*1.A.53 The Hepatitis C Virus P7 Viroporin Cation-selective Channel (HCV-P7) Family |
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*1.A.54 The Presenilin ER Ca<sup>2+</sup> Leak Channel (Presenilin) Family |
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*1.A.55 The Synaptic Vesicle-Associated Ca<sup>2+</sup> Channel, Flower (Flower) Family |
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*1.A.56 The Copper Transporter (Ctr) Family |
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*1.A.57 The Human SARS Coronavirus Viroporin (SARS-VP) |
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*1.A.58 The Type B Influenza Virus Matrix Protein 2 (BM2-C) Family |
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*1.A.59 The Bursal Disease Virus Pore-Forming Peptide, Pep46 (Pep46) Family |
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*1.A.60 The Mammalian Reovirus Pre-forming Peptide, Mu-1 (Mu-1) Family |
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*1.A.61 The Insect Nodavirus Channel-forming Chain F (Gamma-Peptide) Family |
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*1.A.62 The Homotrimeric Cation Channel (TRIC) Family |
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*1.A.63 The Ignicoccus Outer Membrane α-helical Porin (I-OMP Family |
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*1.A.64 The Plasmolipin (Plasmolipin) Family |
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*1.A.65 The Coronavirus Viroporin E Protein (Viroporin E) Family |
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*1.A.66 The Pardaxin (Pardaxin) Family |
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*1.A.67 The Membrane Mg<sup>2+</sup> Transporter (MMgT) Family |
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*1.A.68 The Viral Small Hydrophobic Viroporin (V-SH) Family |
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*1.A.69 The Heteromeric Odorant Receptor Channel (HORC) Family |
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*1.A.70 The Molecule Against Microbes A (MamA) Family |
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*1.A.71 The Brain Acid-soluble Protein Channel (BASP1 Channel) Family |
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*1.A.72 The Mer Superfamily |
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*1.A.73 The Colicin Lysis Protein (CLP) Family |
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*1.A.74 The Mitsugumin 23 (MG23) Family |
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*1.A.75 The Mechanical Nociceptor, Piezo (Piezo) Family |
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*1.A.76 The Magnesium Transporter1 (MagT1) Family |
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*1.A.77 The Mg<sup>2+</sup>/Ca<sup>2+</sup> Uniporter (MCU) Family |
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*1.A.78 The K<sup>+</sup>-selective Channel in Endosomes and Lysosomes (KEL) Family |
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*1.A.79 The Cholesterol Uptake Protein (ChUP) or Double Stranded RNA Uptake Family |
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*1.A.80 The NS4a Viroporin (NS4a) Family |
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*1.A.81 The Low Affinity Ca<sup>2+</sup> Channel (LACC) Family |
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*1.A.82 The Hair Cell Mechanotransduction Channel (HCMC) Family |
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*1.A.83 The SV40 Virus Viroporin VP2 (SV40 VP2) Family |
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*1.A.84 The Calcium Homeostasis Modulator Ca<sup>2+</sup> Channel (CALHM-C) Family |
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*1.A.85 The Poliovirus 2B Viroporin (2B Viroporin) Family |
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*1.A.86 The Human Papilloma Virus type 16 (HPV16) L2 Viroporin (L2 Viroporin) Family |
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*1.A.87 The Mechanosensitive Calcium Channel (MCA) Family |
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*1.A.88 The Fungal Potassium Channel (F-Kch) Family |
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*1.A.89 The Human Coronavirus 229E Viroporin (229E Viroporin) Family |
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*1.A.90 The Human Metapneumovirus (HMPV) Viroporin (HMPV-Viroporin) Family |
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*1.A.91 The Cytoadherence-linked Asexual Protein 3.2 of Plasmodium falciparum (Clag3) Family |
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*1.A.92 The Reovirus Viroporin VP10 (RVP10) Family |
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*1.A.93 The Bluetongue Virus Non-Structural Protein 3 Viroporin (NS3) Family |
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*1.A.94 The Rotavirus Non-structural Glycoprotein 4 Viroporin (NSP4) Family |
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*1.A.95 The Ephemerovirus Viroporin (EVVP) Family |
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*1.A.96 The Human Polyoma Virus Viroporin (PVVP) Family |
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*1.A.97 The Human Papillomavirus type 16 E5 Viroporin (HPV-E5) Family |
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*1.A.98 Human T-Lymphotropic Virus 1 P13 protein (HTLV1-P13) Family |
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*1.A.99 The Infectious Bronchitis Virus Envelope Small Membrane Protein E (IBV-E) Family |
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*1.A.100 The Rhabdoviridae Putative Viroporin, U5 (RV-U5) Family |
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*1.A.101 The Peroxisomal Pore-forming Pex11 (Pex11) Family |
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*1.A.102 Influenza A viroporin PB1-F2 (PB1-F2) Family |
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*1.A.103 The Simian Virus 5 (Parainfluenza Virus 5) SH (SV5-SH) Family |
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*1.A.104 The Proposed Flagellar Biosynthesis Na<sup>+</sup> Channel, FlaH (FlaH) Family |
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*1.A.105 The Mixed Lineage Kinase Domain-like (MLKL) Family |
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*1.A.106 The Calcium Load-activated Calcium Channel (CLAC) Family |
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*1.A.107 The Pore-forming Globin (Globin) Family |
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====1.B. [[Porin (protein)|β-Barrel porins]] and other outer membrane proteins==== |
====1.B. [[Porin (protein)|β-Barrel porins]] and other outer membrane proteins==== |
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* 1.B.23 Cyanobacterial porin (CBP) family |
* 1.B.23 Cyanobacterial porin (CBP) family |
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* 1.B.24 [[Mycobacterial porin]] |
* 1.B.24 [[Mycobacterial porin]] |
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* 1.B.25 Outer membrane porin (Opr) family |
* 1.B.25 [[Outer membrane porin D|Outer membrane porin (Opr) family]] |
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* 1.B.26 Cyclodextrin porin (CDP) family |
* 1.B.26 Cyclodextrin porin (CDP) family |
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* 1.B.31 [[Campylobacter jejuni]] major outer membrane |
* 1.B.31 [[Campylobacter jejuni]] major outer membrane porin (MomP) family |
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* 1.B.32 Fusobacterial outer membrane porin (FomP) family |
* 1.B.32 Fusobacterial outer membrane porin (FomP) family |
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* 1.B.33 Outer membrane protein insertion porin (Bam complex) (OmpIP) family |
* 1.B.33 Outer membrane protein insertion porin (Bam complex) (OmpIP) family |
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* 1.B.44 Probable protein translocating porphyromonas gingivalis porin (PorT) family |
* 1.B.44 Probable protein translocating porphyromonas gingivalis porin (PorT) family |
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* 1.B.49 Anaplasma P44 (A-P44) porin family |
* 1.B.49 Anaplasma P44 (A-P44) porin family |
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* 1.B.48 Curli-like transporters |
* 1.B.48 Curli-like transporters |
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* 1.B.54 [[Intimin]]/Invasin (Int/Inv) or [[Autotransporter domain|Autotransporter-3]] family |
* 1.B.54 [[Intimin]]/Invasin (Int/Inv) or [[Autotransporter domain|Autotransporter-3]] family |
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* 1.B.55 Poly-acetyl-D-glucosamine porin (PgaA) family |
* 1.B.55 Poly-acetyl-D-glucosamine porin (PgaA) family |
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* 1.B.57 Legionella major-outer membrane protein (LM-OMP) family |
* 1.B.57 Legionella major-outer membrane protein (LM-OMP) family |
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* 1.B.60 Omp50 porin (Omp50 Porin) family |
* 1.B.60 Omp50 porin (Omp50 Porin) family |
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* 1.B.71 Proteobacterial/verrucomicrobial porin (PVP) family |
* 1.B.71 Proteobacterial/verrucomicrobial porin (PVP) family |
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* 1.B.72 Protochlamydial outer membrane porin (PomS/T) family |
* 1.B.72 Protochlamydial outer membrane porin (PomS/T) family |
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* 1.B.73 Capsule biogenesis/assembly (CBA) family |
* 1.B.73 Capsule biogenesis/assembly (CBA) family |
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* 1.B.78 DUF3374 electron transport-associated porin (ETPorin) family |
* 1.B.78 DUF3374 electron transport-associated porin (ETPorin) family |
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* 1.C.56 [[HrpZ Family|''Pseudomonas syringae'' HrpZ cation channel family]] |
* 1.C.56 [[HrpZ Family|''Pseudomonas syringae'' HrpZ cation channel family]] |
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* 1.C.57 [[Clostridial Cytotoxin family|Clostridial cytotoxin family]] |
* 1.C.57 [[Clostridial Cytotoxin family|Clostridial cytotoxin family]] |
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*1.C.58 [[Microcin|The Microcin E492/C24 (Microcin E492) Family]] |
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* 1.C.74 [[Snake venom|Snake cytotoxin]] (SCT) family |
* 1.C.74 [[Snake venom|Snake cytotoxin]] (SCT) family |
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* 1.C.97 [[Pleurotolysin|Pleurotolysin pore-forming family]] |
* 1.C.97 [[Pleurotolysin|Pleurotolysin pore-forming family]] |
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* 1.D.4 The Tolaasin Channel-forming Family |
* 1.D.4 The Tolaasin Channel-forming Family |
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* 1.D.5 The [[Alamethicin]] or [[Peptaibol]] Antibiotic Channel-forming Family |
* 1.D.5 The [[Alamethicin]] or [[Peptaibol]] Antibiotic Channel-forming Family |
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* 1.D.6 The Complexed Poly 3-Hydroxybutyrate |
* 1.D.6 The Complexed Poly 3-Hydroxybutyrate Ca<sup>2+</sup> Channel (cPHB-CC) Family |
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* 1.D.7 The Beticolin Family |
* 1.D.7 The Beticolin Family |
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* 1.D.8 The [[Saponin]] Family |
* 1.D.8 The [[Saponin]] Family |
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* 1.D.17 Combinatorially-designed, Pore-forming, β-sheet Peptide Family |
* 1.D.17 Combinatorially-designed, Pore-forming, β-sheet Peptide Family |
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* 1.D.18 The Pore-forming Guanosine-Bile Acid Conjugate Family |
* 1.D.18 The Pore-forming Guanosine-Bile Acid Conjugate Family |
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* 1.D.19 |
* 1.D.19 Ca<sup>2+</sup> Channel-forming Drug, [[Digitoxin]] Family |
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* 1.D.20 The Pore-forming Polyene Macrolide Antibiotic/fungal Agent (PMAA) Family |
* 1.D.20 The Pore-forming Polyene Macrolide Antibiotic/fungal Agent (PMAA) Family |
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* 1.D.21 The Lipid Nanopore (LipNP) Family |
* 1.D.21 The Lipid Nanopore (LipNP) Family |
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* 1.D.58 The Anion Transporting Prodigiosene (Prodigiosene) Family |
* 1.D.58 The Anion Transporting Prodigiosene (Prodigiosene) Family |
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* 1.D.59 The Anion Transporting Perenosin (Perenosin) Family |
* 1.D.59 The Anion Transporting Perenosin (Perenosin) Family |
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* 1.D.60 The Alpha,Gamma- |
* 1.D.60 The Alpha,Gamma-Cyclic Peptide (AGCP) Family |
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* 1.D.61 The Anionophoric 2,6-Bis(Benzimidazol-2-yl)Pyridine (ABBP) Family |
* 1.D.61 The Anionophoric {{Chem name|2,6-Bis(Benzimidazol-2-yl)Pyridine}} (ABBP) Family |
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* 1.D.62 The Bis-Triazolyl DiGuanosine Derivative Channel-forming (TDG) Family |
* 1.D.62 The Bis-Triazolyl DiGuanosine Derivative Channel-forming (TDG) Family |
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* 1.D.63 The Peptide-based Nanopore (PepNP) Family |
* 1.D.63 The Peptide-based Nanopore (PepNP) Family |
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====2.A Porters ([[uniporter]]s, [[symporter]]s, [[antiporter]]s)==== |
====2.A Porters ([[uniporter]]s, [[symporter]]s, [[antiporter]]s)==== |
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{{also|Amino acid transporter}} |
{{see also|Amino acid transporter}} |
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*2.A.1 [[Major facilitator superfamily|Major Facilitator superfamily]] (MFS), see also [[Lactose permease]], [[Phosphate permease]] and [[Glucose transporter]] |
*2.A.1 [[Major facilitator superfamily|Major Facilitator superfamily]] (MFS), see also [[Lactose permease]], [[Phosphate permease]] and [[Glucose transporter]] |
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*2.A.2 [[Glycoside-pentoside-hexuronide:cation symporter family|The Glycoside-Pentoside-Hexuronide (GPH):Cation Symporter Family]] |
*2.A.2 [[Glycoside-pentoside-hexuronide:cation symporter family|The Glycoside-Pentoside-Hexuronide (GPH):Cation Symporter Family]] |
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*2.A.3 [[APC superfamily|The Amino Acid-Polyamine-Organocation (APC) Family]] |
*2.A.3 [[APC superfamily|The Amino Acid-Polyamine-Organocation (APC) Family]] |
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*2.A.4 |
*2.A.4 [[Cation diffusion facilitator]] (CDF) Family |
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*2.A.5 |
*2.A.5 [[Ferroportin|Zinc (Zn<sup>2+</sup>)-Iron (Fe<sup>2+</sup>) Permease]] Family |
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*2.A.6 [[Resistance-nodulation-cell division superfamily|Resistance-Nodulation-Cell Division Superfamily]] |
*2.A.6 [[Resistance-nodulation-cell division superfamily|Resistance-Nodulation-Cell Division Superfamily]], see also [[SecDF protein-export membrane protein]] |
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*2.A.7 The [[Small multidrug resistance protein|Drug/Metabolite Transporter]] (DMT) Superfamily |
*2.A.7 The [[Small multidrug resistance protein|Drug/Metabolite Transporter]] (DMT) Superfamily |
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*2.A.8 The Gluconate:H+ Symporter (GntP) Family |
*2.A.8 The Gluconate:H<sup>+</sup> Symporter (GntP) Family |
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*2.A.9 The Membrane Protein Insertase (YidC/Alb3/Oxa1) Family |
*2.A.9 The Membrane Protein Insertase (YidC/Alb3/Oxa1) Family |
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*2.A.10 The 2-Keto-3-Deoxygluconate Transporter (KdgT) Family |
*2.A.10 The 2-Keto-3-Deoxygluconate Transporter (KdgT) Family |
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*2.A.11 The Citrate- |
*2.A.11 The Citrate-Mg<sup>2+</sup>:H<sup>+</sup> (CitM) Citrate-Ca<sup>2+</sup>:H<sup>+</sup> (CitH) Symporter (CitMHS) Family |
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*2.A.12 [[ATP:ADP antiporter family|ATP:ADP Antiporter Family]] |
*2.A.12 [[ATP:ADP antiporter family|ATP:ADP Antiporter Family]] |
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*2.A.13 The C4-Dicarboxylate Uptake (Dcu) Family |
*2.A.13 The C4-Dicarboxylate Uptake (Dcu) Family |
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*2.A.14 [[Lactate permease family|Lactate Permease Family]] |
*2.A.14 [[Lactate permease family|Lactate Permease Family]] |
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*2.A.15 [[Betaine transporter|The Betaine/Carnitine/Choline Transporter (BCCT) Family]] |
*2.A.15 [[Betaine transporter|The Betaine/Carnitine/Choline Transporter (BCCT) Family]] |
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*2.A.16 [[Tellurite-resistance/dicarboxylate transporter| |
*2.A.16 [[Tellurite-resistance/dicarboxylate transporter|Tellurite-resistance/Dicarboxylate Transporter]] Family |
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*2.A.17 [[Proton-dependent oligopeptide transporter|Proton-dependent Oligopeptide Transporter Family]] |
*2.A.17 [[Proton-dependent oligopeptide transporter|Proton-dependent Oligopeptide Transporter Family]] |
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*2.A.18 The Amino Acid/Auxin Permease (AAAP) Family |
*2.A.18 The Amino Acid/Auxin Permease (AAAP) Family |
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*2.A.19 The |
*2.A.19 The Ca<sup>2+</sup>:Cation Antiporter (CaCA) Family |
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*2.A.20 The Inorganic Phosphate Transporter (PiT) Family |
*2.A.20 The Inorganic Phosphate Transporter (PiT) Family |
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*2.A.21 [[Sodium-solute symporter|Solute:Sodium Symporter Family]] |
*2.A.21 [[Sodium-solute symporter|Solute:Sodium Symporter Family]] |
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*2.A.22 The [[Neurotransmitter sodium symporter|Neurotransmitter:Sodium Symporter]] Family |
*2.A.22 The [[Neurotransmitter sodium symporter|Neurotransmitter:Sodium Symporter]] Family |
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*2.A.23 The Dicarboxylate/Amino Acid:Cation (Na+ or H+) Symporter (DAACS) Family |
*2.A.23 The Dicarboxylate/Amino Acid:Cation (Na<sup>+</sup> or H<sup>+</sup>) Symporter (DAACS) Family |
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*2.A.24 The 2-Hydroxycarboxylate Transporter (2-HCT) Family |
*2.A.24 The 2-Hydroxycarboxylate Transporter (2-HCT) Family |
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*2.A.25 [[AGCS family|Alanine or Glycine:Cation Symporter]] (AGCS) Family |
*2.A.25 [[AGCS family|Alanine or Glycine:Cation Symporter]] (AGCS) Family |
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*2.A.26 The Branched Chain Amino Acid:Cation Symporter (LIVCS) Family |
*2.A.26 The Branched Chain Amino Acid:Cation Symporter (LIVCS) Family |
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*2.A.27 The Glutamate:Na+ Symporter (ESS) Family |
*2.A.27 The Glutamate:Na<sup>+</sup> Symporter (ESS) Family |
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*2.A.28 [[Bile acid:sodium symporter|Bile Acid:Na+ Symporter]] Family |
*2.A.28 [[Bile acid:sodium symporter|Bile Acid:Na<sup>+</sup> Symporter]] Family |
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*2.A.29 [[Mitochondrial carrier]] Family |
*2.A.29 [[Mitochondrial carrier]] Family |
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*2.A.30 [[Chloride potassium symporter|Cation-Chloride Cotransporter]] (CCC) Family |
*2.A.30 [[Chloride potassium symporter|Cation-Chloride Cotransporter]] (CCC) Family |
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*2.A.31 [[Anion exchanger family|Anion Exchanger |
*2.A.31 [[Anion exchanger family|Anion Exchanger Family]] |
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*2.A.32 The Silicon Transporter (Sit) Family |
*2.A.32 The Silicon Transporter (Sit) Family |
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*2.A.33 [[Sodium-proton antiporter|NhaA Na+:H+ Antiporter]] (NhaA) Family |
*2.A.33 [[Sodium-proton antiporter|NhaA Na<sup>+</sup>:H<sup>+</sup> Antiporter]] (NhaA) Family |
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*2.A.34 The NhaB Na+:H+ Antiporter (NhaB) Family |
*2.A.34 The NhaB Na<sup>+</sup>:H<sup>+</sup> Antiporter (NhaB) Family |
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*2.A.35 The NhaC Na+:H+ Antiporter (NhaC) Family |
*2.A.35 The NhaC Na<sup>+</sup>:H<sup>+</sup> Antiporter (NhaC) Family |
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*2.A.36 [[Monovalent cation:proton antiporter-1|Monovalent Cation:Proton Antiporter-1]] (CPA1) Family |
*2.A.36 [[Monovalent cation:proton antiporter-1|Monovalent Cation:Proton Antiporter-1]] (CPA1) Family |
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*2.A.37 [[Monovalent cation:proton antiporter- |
*2.A.37 [[Monovalent cation:proton antiporter-2|Monovalent Cation:Proton Antiporter-2]] (CPA2) Family |
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*2.A.38 [[Potassium transporter family|K+ Transporter (Trk)]] Family |
*2.A.38 [[Potassium transporter family|K<sup>+</sup> Transporter (Trk)]] Family |
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*2.A.39 [[Nucleobase cation symporter-1|Nucleobase:Cation Symporter-1]] (NCS1) Family |
*2.A.39 [[Nucleobase cation symporter-1|Nucleobase:Cation Symporter-1]] (NCS1) Family |
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*2.A.40 |
*2.A.40 [[Nucleobase cation symporter-2|Nucleobase:Cation Symporter-2]] (NCS2) Family |
||
*2.A.41 The Concentrative Nucleoside Transporter (CNT) Family |
*2.A.41 The Concentrative Nucleoside Transporter (CNT) Family |
||
*2.A.42 The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family |
*2.A.42 The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family |
||
*2.A.43 The Lysosomal Cystine Transporter (LCT) Family |
*2.A.43 The Lysosomal Cystine Transporter (LCT) Family |
||
*2.A.45 [[Arsenite-antimonite transporter|Arsenite-Antimonite Efflux Family]] |
*2.A.45 [[Arsenite-antimonite transporter|Arsenite-Antimonite Efflux Family]] |
||
*2.A.46 The Benzoate:H+ Symporter (BenE) Family |
*2.A.46 The Benzoate:H<sup>+</sup> Symporter (BenE) Family |
||
*2.A.47 [[Divalent anion–sodium symporter|Divalent Anion:Na+ Symporter]] (DASS) Family |
*2.A.47 [[Divalent anion–sodium symporter|Divalent Anion:Na<sup>+</sup> Symporter]] (DASS) Family |
||
*2.A.48 The Reduced Folate Carrier (RFC) Family |
*2.A.48 The Reduced Folate Carrier (RFC) Family |
||
*2.A.49 [[Chloride channel|Chloride Carrier/Channel]] (ClC) Family |
*2.A.49 [[Chloride channel|Chloride Carrier/Channel]] (ClC) Family |
||
*2.A.50 The Glycerol Uptake (GUP) Family |
*2.A.50 The Glycerol Uptake (GUP) Family |
||
*2.A.51 The Chromate Ion Transporter (CHR) Family |
*2.A.51 The Chromate Ion Transporter (CHR) Family |
||
*2.A.52 The |
*2.A.52 The Ni<sup>2+</sup>-Co<sup>2+</sup> Transporter (NiCoT) Family |
||
*2.A.53 |
*2.A.53 [[Sulfate permease]] (SulP) Family |
||
*2.A.54 The Mitochondrial Tricarboxylate Carrier (MTC) Family |
*2.A.54 The Mitochondrial Tricarboxylate Carrier (MTC) Family |
||
*2.A.55 The Metal Ion ( |
*2.A.55 [[Natural Resistance-Associated Macrophage Proteins|The Metal Ion (Mn<sup>2+</sup>-iron) Transporter]] (Nramp) Family |
||
*2.A.56 The Tripartite ATP-independent Periplasmic Transporter (TRAP-T) Family |
*2.A.56 The Tripartite ATP-independent Periplasmic Transporter (TRAP-T) Family |
||
*2.A.57 The Equilibrative Nucleoside Transporter (ENT) Family |
*2.A.57 The Equilibrative Nucleoside Transporter (ENT) Family |
||
*2.A.58 The Phosphate:Na+ Symporter (PNaS) Family |
*2.A.58 The Phosphate:Na<sup>+</sup> Symporter (PNaS) Family |
||
*2.A.59 The Arsenical Resistance-3 (ACR3) Family |
*2.A.59 The Arsenical Resistance-3 (ACR3) Family |
||
*2.A.60 [[Organo anion transporter family|Organo Anion Transporter]] (OAT) Family |
*2.A.60 [[Organo anion transporter family|Organo Anion Transporter]] (OAT) Family |
||
*2.A.61 The C4-dicarboxylate Uptake C (DcuC) Family |
*2.A.61 The C4-dicarboxylate Uptake C (DcuC) Family |
||
*2.A.62 The NhaD Na+:H+ Antiporter (NhaD) Family |
*2.A.62 The NhaD Na<sup>+</sup>:H<sup>+</sup> Antiporter (NhaD) Family |
||
*2.A.63 The Monovalent Cation (K+ or Na+):Proton Antiporter-3 (CPA3) Family |
*2.A.63 [[Monovalent cation:proton antiporter-3|The Monovalent Cation (K<sup>+</sup> or Na<sup>+</sup>):Proton Antiporter-3]] (CPA3) Family |
||
*2.A.64 [[Twin-arginine translocation pathway|Twin Arginine Targeting (Tat) Family]] |
*2.A.64 [[Twin-arginine translocation pathway|Twin Arginine Targeting (Tat) Family]] |
||
*2.A.65 The Bilirubin Transporter (BRT) Family |
*2.A.65 The Bilirubin Transporter (BRT) Family |
||
Line 314: | Line 373: | ||
*2.A.68 The p-Aminobenzoyl-glutamate Transporter (AbgT) Family |
*2.A.68 The p-Aminobenzoyl-glutamate Transporter (AbgT) Family |
||
*2.A.69 The Auxin Efflux Carrier (AEC) Family |
*2.A.69 The Auxin Efflux Carrier (AEC) Family |
||
*2.A.70 The Malonate:Na+ Symporter (MSS) Family |
*2.A.70 The Malonate:Na<sup>+</sup> Symporter (MSS) Family |
||
*2.A.71 The Folate-Biopterin Transporter (FBT) Family |
*2.A.71 The Folate-Biopterin Transporter (FBT) Family |
||
*2.A.72 The K+ Uptake Permease (KUP) Family |
*2.A.72 The K<sup>+</sup> Uptake Permease (KUP) Family |
||
*2.A.73 The Short Chain Fatty Acid Uptake (AtoE) Family |
*2.A.73 The Short Chain Fatty Acid Uptake (AtoE) Family |
||
*2.A.74 The 4 TMS Multidrug Endosomal Transporter (MET) Family |
*2.A.74 The 4 TMS Multidrug Endosomal Transporter (MET) Family |
||
Line 327: | Line 386: | ||
*2.A.81 The Aspartate:Alanine Exchanger (AAEx) Family |
*2.A.81 The Aspartate:Alanine Exchanger (AAEx) Family |
||
*2.A.82 The Organic Solute Transporter (OST) Family |
*2.A.82 The Organic Solute Transporter (OST) Family |
||
*2.A.83 The Na+-dependent Bicarbonate Transporter (SBT) Family |
*2.A.83 The Na<sup>+</sup>-dependent Bicarbonate Transporter (SBT) Family |
||
*2.A.84 The Chloroplast Maltose Exporter (MEX) Family |
*2.A.84 The Chloroplast Maltose Exporter (MEX) Family |
||
*2.A.85 The Aromatic Acid Exporter (ArAE) Family |
*2.A.85 The Aromatic Acid Exporter (ArAE) Family |
||
Line 340: | Line 399: | ||
*2.A.95 The 6TMS Neutral Amino Acid Transporter (NAAT) Family |
*2.A.95 The 6TMS Neutral Amino Acid Transporter (NAAT) Family |
||
*2.A.96 The Acetate Uptake Transporter (AceTr) Family |
*2.A.96 The Acetate Uptake Transporter (AceTr) Family |
||
*2.A.97 The Mitochondrial Inner Membrane K+/H+ and |
*2.A.97 The Mitochondrial Inner Membrane K<sup>+</sup>/H<sup>+</sup> and Ca<sup>2+</sup>/H<sup>+</sup> Exchanger (LetM1) Family |
||
*2.A.98 The Putative Sulfate Exporter (PSE) Family |
*2.A.98 The Putative Sulfate Exporter (PSE) Family |
||
*2.A.99 The 6TMS |
*2.A.99 The 6TMS Ni<sup>2+</sup> uptake transporter (HupE-UreJ) Family |
||
*2.A.100 The Ferroportin (Fpn) Family |
*2.A.100 The Ferroportin (Fpn) Family |
||
*2.A.101 The Malonate Uptake (MatC) Family (Formerly UIT1) |
*2.A.101 The Malonate Uptake (MatC) Family (Formerly UIT1) |
||
Line 349: | Line 408: | ||
*2.A.104 The L-Alanine Exporter (AlaE) Family |
*2.A.104 The L-Alanine Exporter (AlaE) Family |
||
*2.A.105 The Mitochondrial Pyruvate Carrier (MPC) Family |
*2.A.105 The Mitochondrial Pyruvate Carrier (MPC) Family |
||
*2.A.106 The |
*2.A.106 The Ca<sup>2+</sup>:H<sup>+</sup> Antiporter-2 (CaCA2) Family |
||
*2.A.107 The MntP |
*2.A.107 The MntP Mn<sup>2+</sup> Exporter (MntP) Family |
||
*2.A.108 The Iron/Lead Transporter (ILT) Family |
*2.A.108 The Iron/Lead Transporter (ILT) Family |
||
*2.A.109 The Tellurium Ion Resistance (TerC) Family |
*2.A.109 The Tellurium Ion Resistance (TerC) Family |
||
*2.A.110 The |
*2.A.110 The Heme Transporter, heme-responsive gene protein (HRG) Family |
||
*2.A.111 The Na+/H+ Antiporter-E (NhaE) Family |
*2.A.111 The Na<sup>+</sup>/H<sup>+</sup> Antiporter-E (NhaE) Family |
||
*2.A.112 The KX Blood-group Antigen (KXA) Family |
*2.A.112 The KX Blood-group Antigen (KXA) Family |
||
*2.A.113 The Nickel/cobalt Transporter (NicO) Family |
*2.A.113 The Nickel/cobalt Transporter (NicO) Family |
||
Line 365: | Line 424: | ||
*2.A.120 The Putative Amino Acid Permease (PAAP) Family |
*2.A.120 The Putative Amino Acid Permease (PAAP) Family |
||
*2.A.121 The Sulfate Transporter (CysZ) Family |
*2.A.121 The Sulfate Transporter (CysZ) Family |
||
*2.A.122 The LrgB/CidB holin-like |
*2.A.122 The LrgB/CidB holin-like auxiliary protein (LrgB/CidB) Family |
||
*2.A.123 The Sweet; PQ-loop; Saliva; MtN3 (Sweet) Family |
*2.A.123 The Sweet; PQ-loop; Saliva; MtN3 (Sweet) Family |
||
*2.A.124 The Lysine Exporter (LysO) Family |
*2.A.124 The Lysine Exporter (LysO) Family |
||
Line 382: | Line 441: | ||
*2.B.8 The [[Bafilomycin]] A1 (Bafilomycin) Family |
*2.B.8 The [[Bafilomycin]] A1 (Bafilomycin) Family |
||
*2.B.9 The [[Cell Penetrating Peptide]] (CPP) Functional Family |
*2.B.9 The [[Cell Penetrating Peptide]] (CPP) Functional Family |
||
*2.B.10 The Synthetic CPP, [[Transportan]]Family |
*2.B.10 The Synthetic CPP, [[Transportan]] Family |
||
*2.B.11 The [[Calcimycin]] or A23187 Carrier-type Ionophore Family |
*2.B.11 The [[Calcimycin]] or A23187 Carrier-type Ionophore Family |
||
*2.B.12 The [[Salinomycin]] Family |
*2.B.12 The [[Salinomycin]] Family |
||
Line 389: | Line 448: | ||
*2.B.15 The Tris-thiourea Tripodal-based Chloride Carrier (TTT-CC) Family |
*2.B.15 The Tris-thiourea Tripodal-based Chloride Carrier (TTT-CC) Family |
||
*2.B.16 The Halogen-bond-containing Compound Anion Carrier (HCAC) Family |
*2.B.16 The Halogen-bond-containing Compound Anion Carrier (HCAC) Family |
||
*2.B.17 The Isophthalaminde Derivative H+:Cl |
*2.B.17 The Isophthalaminde Derivative H<sup>+</sup>:Cl<sup>−</sup> Co-transporter (IDC) Family |
||
*2.B.18 The Pyridine-2,6-Dicarboxamine Derivative (PDCA) H+:Cl |
*2.B.18 The Pyridine-2,6-Dicarboxamine Derivative (PDCA) H+:Cl<sup>−</sup> Co-transporter Family |
||
*2.B.19 The Calix(4)pyrrole Derivative (C4P) Family |
*2.B.19 The Calix(4)pyrrole Derivative (C4P) Family |
||
*2.B.20 The Prodigiosin (Prodigiosin) Chloride/Bicarbonate Exchanger Family |
*2.B.20 The Prodigiosin (Prodigiosin) Chloride/Bicarbonate Exchanger Family |
||
*2.B.21 The ortho-Phenylenediamine-bis-Urea Derivative Anion Transporter (oPDA-U) Family |
*2.B.21 The ortho-Phenylenediamine-bis-Urea Derivative Anion Transporter (oPDA-U) Family |
||
*2.B.22 The Imidazolium-functionalized Anion Transporter (IAT) Family |
*2.B.22 The Imidazolium-functionalized Anion Transporter (IAT) Family |
||
*2.B.23 The Homotetrameric Transmembrane |
*2.B.23 The Homotetrameric Transmembrane Zn<sup>2+</sup>/Co<sup>2+</sup>:Proton Synthetic Antiporter, Rocker (Rocker) Family |
||
*2.B.24 The 2,6-Bis(benzimidazol-2-yl)pyridine Anion Carrier (BBP-AC) Family |
*2.B.24 The {{Chem name|2,6-Bis(benzimidazol-2-yl)pyridine}} Anion Carrier (BBP-AC) Family |
||
*2.B.25 The Peptide-mediated Lipid Flip-Flop (PLFF) Family |
*2.B.25 The Peptide-mediated Lipid Flip-Flop (PLFF) Family |
||
*2.B.26 The Bis(imidazolyl)-functionalized Bis(Choloyl) Conjugate (BIBCC) Family |
*2.B.26 The {{Not a typo|Bis(imidazolyl)-functionalized}} {{Not a typo|Bis(Choloyl)}} Conjugate (BIBCC) Family |
||
*2.B.27 The Tris-Urea Anion Transporter Family |
*2.B.27 The Tris-Urea Anion Transporter Family |
||
*2.B.29 The Anionophoric Marine Alkaloid [[Tambjamine]] Family |
*2.B.29 The Anionophoric Marine Alkaloid [[Tambjamine]] Family |
||
Line 405: | Line 464: | ||
*2.C.1 The TonB-ExbB-ExbD/TolA-TolQ-TolR (TonB) Family of Auxiliary Proteins for Energization of Outer Membrane Receptor (OMR)-mediated Active Transport |
*2.C.1 The TonB-ExbB-ExbD/TolA-TolQ-TolR (TonB) Family of Auxiliary Proteins for Energization of Outer Membrane Receptor (OMR)-mediated Active Transport |
||
===3. [[Primary active transport |
===3. [[Primary active transport]]ers=== |
||
====3.A. P-P-bond hydrolysis-driven transporters==== |
====3.A. P-P-bond hydrolysis-driven transporters==== |
||
*3.A.1 [[ABC transporter]]s including BtuCD, molybdate uptake transporter, [[Cystic fibrosis transmembrane conductance regulator]] and others |
*3.A.1 [[ABC transporter]]s including BtuCD, molybdate uptake transporter, [[Cystic fibrosis transmembrane conductance regulator]] and others |
||
*3.A.2 The H+- or Na+-translocating F-type, V-type and A-type ATPase |
*3.A.2 The H<sup>+</sup>- or Na<sup>+</sup>-translocating [[F-type ATPase]], [[V-type ATPase]] and A-type ATPase superfamily |
||
*3.A.3 [[P-type ATPase|The P-type ATPase]] Superfamily |
*3.A.3 [[P-type ATPase|The P-type ATPase]] Superfamily |
||
*3.A.4 The Arsenite-Antimonite |
*3.A.4 [[ArsB and ArsAB transporters|The Arsenite-Antimonite efflux]] family |
||
*3.A.5 [[SecY protein|General secretory pathway]] (Sec) [[translocon]] (preprotein translocase SecY) |
*3.A.5 [[SecY protein|General secretory pathway]] (Sec) [[translocon]] (preprotein translocase SecY) |
||
*3.A.6 The Type III (Virulence-related) Secretory Pathway (IIISP) Family |
*3.A.6 The Type III (Virulence-related) Secretory Pathway (IIISP) Family |
||
Line 417: | Line 476: | ||
*3.A.8 The Mitochondrial Protein Translocase (MPT) Family |
*3.A.8 The Mitochondrial Protein Translocase (MPT) Family |
||
*3.A.9 The Chloroplast Envelope Protein Translocase (CEPT or Tic-Toc) Family |
*3.A.9 The Chloroplast Envelope Protein Translocase (CEPT or Tic-Toc) Family |
||
*3.A.10 |
*3.A.10 [[H+, Na+-translocating pyrophosphatase family|H<sup>+</sup>, Na<sup>+</sup>-translocating Pyrophosphatase]] family |
||
*3.A.11 The Bacterial Competence-related DNA Transformation Transporter (DNA-T) Family |
*3.A.11 The Bacterial Competence-related DNA Transformation Transporter (DNA-T) Family |
||
*3.A.12 The Septal DNA Translocator (S-DNA-T) Family |
*3.A.12 The Septal DNA Translocator (S-DNA-T) Family |
||
Line 436: | Line 495: | ||
====3.B Decarboxylation-driven transporters==== |
====3.B Decarboxylation-driven transporters==== |
||
*3.B.1 The Na+-transporting Carboxylic Acid Decarboxylase (NaT-DC) Family |
*3.B.1 The Na<sup>+</sup>-transporting Carboxylic Acid Decarboxylase (NaT-DC) Family |
||
====3.C Methyltransfer-driven transporters==== |
====3.C Methyltransfer-driven transporters==== |
||
*3.C.1 The Na+ Transporting Methyltetrahydromethanopterin:Coenzyme M Methyltransferase (NaT-MMM) Family |
*3.C.1 The Na<sup>+</sup> Transporting Methyltetrahydromethanopterin:Coenzyme M Methyltransferase (NaT-MMM) Family |
||
====3.D. Oxidoreduction-driven transporters==== |
====3.D. Oxidoreduction-driven transporters==== |
||
They include a number of transmembrane [[cytochrome b]]-like proteins including [[coenzyme Q - cytochrome c reductase]] (cytochrome bc1 ); [[cytochrome b6f complex]]; formate dehydrogenase, respiratory [[nitrate reductase]]; [[succinate - coenzyme Q reductase]] (fumarate reductase); and [[succinate dehydrogenase]]. See [[electron transport chain]]. |
They include a number of transmembrane [[cytochrome b]]-like proteins including [[coenzyme Q - cytochrome c reductase]] (cytochrome bc1 ); [[cytochrome b6f complex]]; formate dehydrogenase, respiratory [[nitrate reductase]]; [[succinate - coenzyme Q reductase]] (fumarate reductase); and [[succinate dehydrogenase]]. See [[electron transport chain]]. |
||
*3.D.1 [[NADH:ubiquinone reductase (H+-translocating)|The H+ or Na+-translocating NADH Dehydrogenase]] ("complex I") family |
*3.D.1 [[NADH:ubiquinone reductase (H+-translocating)|The H<sup>+</sup> or Na<sup>+</sup>-translocating NADH Dehydrogenase]] ("complex I") family |
||
*3.D.2 The Proton-translocating Transhydrogenase (PTH) Family |
*3.D.2 The Proton-translocating Transhydrogenase (PTH) Family |
||
*3.D.3 [[Cytochrome c nitrite reductase|The Proton-translocating Quinol:Cytochrome c Reductase]]) Superfamily |
*3.D.3 [[Cytochrome c nitrite reductase|The Proton-translocating Quinol:Cytochrome c Reductase]]) Superfamily |
||
*3.D.4 [[Cytochrome c oxidase|Proton-translocating Cytochrome Oxidase]] (COX) Superfamily |
*3.D.4 [[Cytochrome c oxidase|Proton-translocating Cytochrome Oxidase]] (COX) Superfamily |
||
*3.D.5 The Na+-translocating NADH:Quinone Dehydrogenase (Na-NDH or NQR) Family |
*3.D.5 The Na<sup>+</sup>-translocating NADH:Quinone Dehydrogenase (Na-NDH or NQR) Family |
||
*3.D.6 The Putative Ion (H+ or Na+)-translocating NADH:Ferredoxin Oxidoreductase (NFO or RNF) Family |
*3.D.6 The Putative Ion (H<sup>+</sup> or Na<sup>+</sup>)-translocating NADH:Ferredoxin Oxidoreductase (NFO or RNF) Family |
||
*3.D.7 The |
*3.D.7 The H<sub>2</sub>:Heterodisulfide Oxidoreductase (HHO) Family |
||
*3.D.8 The Na+- or H+-Pumping Formyl Methanofuran Dehydrogenase (FMF-DH) Family |
*3.D.8 The Na<sup>+</sup>- or H<sup>+</sup>-Pumping Formyl Methanofuran Dehydrogenase (FMF-DH) Family |
||
*3.D.9 The H+-translocating F420H2 Dehydrogenase (F420H2DH) Family |
*3.D.9 The H<sup>+</sup>-translocating F420H2 Dehydrogenase (F420H2DH) Family |
||
*3.D.10 The Prokaryotic Succinate Dehydrogenase (SDH) Family |
*3.D.10 The Prokaryotic Succinate Dehydrogenase (SDH) Family |
||
Line 470: | Line 529: | ||
*4.A.4 The PTS Glucitol (Gut) Family |
*4.A.4 The PTS Glucitol (Gut) Family |
||
*4.A.5 The PTS Galactitol (Gat) Family |
*4.A.5 The PTS Galactitol (Gat) Family |
||
*4.A.6 The PTS Mannose-Fructose-Sorbose (Man) Family |
*4.A.6 [[PTS Mannose-Fructose-Sorbose Family|The PTS Mannose-Fructose-Sorbose (Man) Family]] |
||
*4.A.7 The PTS L-Ascorbate (L-Asc) Family |
*4.A.7 The PTS L-Ascorbate (L-Asc) Family |
||
Line 496: | Line 555: | ||
====5.B Transmembrane 1-electron transfer carriers==== |
====5.B Transmembrane 1-electron transfer carriers==== |
||
*5.B.1 The Phagocyte (gp91phox) NADPH Oxidase Family |
*5.B.1 The Phagocyte ([[gp91phox]]) [[NADPH oxidase|NADPH Oxidase]] Family |
||
*5.B.2 The Eukaryotic Cytochrome b561 (Cytb561) Family |
*5.B.2 The Eukaryotic [[Cytochrome b561]] (Cytb561) Family |
||
*5.B.3 The Geobacter Nanowire Electron Transfer (G-NET) Family |
*5.B.3 The Geobacter Nanowire Electron Transfer (G-NET) Family |
||
*5.B.4 The Plant Photosystem I Supercomplex (PSI) Family |
*5.B.4 The Plant Photosystem I Supercomplex (PSI) Family |
||
*5.B.5 The Extracellular Metal Oxido-Reductase (EMOR) Family |
*5.B.5 The Extracellular Metal Oxido-Reductase (EMOR) Family |
||
*5.B.6 The Transmembrane Epithelial Antigen |
*5.B.6 The [[STEAP3|Transmembrane Epithelial Antigen Protein-3]] Ferric Reductase (STEAP) Family |
||
*5.B.7 The YedZ (YedZ) Family |
*5.B.7 The [[YedZ family|YedZ (YedZ) Family]] |
||
*5.B.8 The Trans-Outer Membrane Electron Transfer Porin/Cytochrome Complex (ET-PCC) Family |
*5.B.8 The Trans-Outer Membrane Electron Transfer Porin/Cytochrome Complex (ET-PCC) Family |
||
*5.B.9 The Porin-Cytochrome c (Cyc2) Family |
*5.B.9 The Porin-Cytochrome c (Cyc2) Family |
||
Line 528: | Line 587: | ||
* [http://www.tcdb.org/ Transporter Classification Database] |
* [http://www.tcdb.org/ Transporter Classification Database] |
||
* [http://www.chem.qmul.ac.uk/iubmb/mtp/ List] at qmul.ac.uk |
* [http://www.chem.qmul.ac.uk/iubmb/mtp/ List] at qmul.ac.uk |
||
* {{cite journal |vauthors=Saier MH, Tran CV, Barabote RD |title=TCDB: the Transporter Classification Database for membrane transport protein analyses and information |journal=Nucleic Acids Res. |volume=34 |issue=Database issue |pages=D181–6 |date=January 2006 |pmid=16381841 |pmc=1334385 |doi=10.1093/nar/gkj001 |url= |
* {{cite journal |vauthors=Saier MH, Tran CV, Barabote RD |title=TCDB: the Transporter Classification Database for membrane transport protein analyses and information |journal=Nucleic Acids Res. |volume=34 |issue=Database issue |pages=D181–6 |date=January 2006 |pmid=16381841 |pmc=1334385 |doi=10.1093/nar/gkj001 |url=}} |
||
* {{cite journal |vauthors=Busch W, Saier MH |title=The transporter classification (TC) system, 2002 |journal=Crit. Rev. Biochem. Mol. Biol. |volume=37 |issue=5 |pages=287–337 |year=2002 |pmid=12449427 |doi= 10.1080/10409230290771528| |
* {{cite journal |vauthors=Busch W, Saier MH |title=The transporter classification (TC) system, 2002 |journal=Crit. Rev. Biochem. Mol. Biol. |volume=37 |issue=5 |pages=287–337 |year=2002 |pmid=12449427 |doi= 10.1080/10409230290771528|s2cid=10558982 }} |
||
* [http://www.guidetopharmacology.org/GRAC/ReceptorFamiliesForward?type=TRANSPORTER Classification of human transporters in pharmacology] |
* [http://www.guidetopharmacology.org/GRAC/ReceptorFamiliesForward?type=TRANSPORTER Classification of human transporters in pharmacology] |
||
Line 542: | Line 601: | ||
{{Oxidoreduction-driven transporters}} |
{{Oxidoreduction-driven transporters}} |
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⚫ | |||
[[Category:Transport proteins]] |
[[Category:Transport proteins]] |
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[[Category:Transmembrane proteins]] |
[[Category:Transmembrane proteins]] |
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[[Category: |
[[Category:Protein classification]] |
||
⚫ |
The Transporter Classification Database (orTCDB) is an International Union of Biochemistry and Molecular Biology (IUBMB)-approved classification system for membrane transport proteins, including ion channels.[1][2][3]
The upper level of classification and a few examples of proteins with known 3D structure:
They include a number of transmembrane cytochrome b-like proteins including coenzyme Q - cytochrome c reductase (cytochrome bc1 ); cytochrome b6f complex; formate dehydrogenase, respiratory nitrate reductase; succinate - coenzyme Q reductase (fumarate reductase); and succinate dehydrogenase. See electron transport chain.
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see also disorders |
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Antimicrobial cationic peptides |
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Other, human |
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Other, nonhuman |
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Synaptic vesicle |
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COPI |
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COPII |
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RME/Clathrin |
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Caveolae |
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Other/ungrouped |
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see also solute carrier disorders |
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A |
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B |
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C |
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D |
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E |
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F |
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G |
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see also ABC transporter disorders |
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F-, V-, and A-type ATPase (3.A.2) |
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P-type ATPase (3.A.3) |
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see also ATPase disorders |