February 29 – John Zápolya, ruler of the remaining eastern portion of Hungary after its the acquisition of the western section by the Habsburg Austrians, joins in an alliance with the Sultan Suleiman the Magnificent of the Ottoman Turks, receiving protection and autonomy in return for allowing Turkish occupation of his Eastern Hungarian Kingdom.
March 20 – The Battle of Szina is fought in the Kingdom of Hungary between the two rival kings, John Zápolya of Eastern Hungary and Archduke Ferdinand of Austria, the Habsburg King of Western Hungary. Zapolya and his 15,000-man army are defeated by mercenaries hired by the Habsburgs.
March 22 – siege of the southern Italian city of Melfi is started by the French Army, under the command of Marshal Odet of Foix, Viscount of Lautrec. After killing the defenders and pulling down the city walls, the French troops plunder what remains and massacre more than 3,000 men, women and children.[5]
June 5 – The fourth major outbreak of the sweating sickness is noted for the first time, with a reference in a letter to Bishop Tunstall of London from someone who has fled his home because a servant at his house has become infected with the disease, with sweating soon followed by death.[8]
July 8 – After surviving a mutiny of his crew and the death of 18 of his men in an ambush in what is now Argentina, Italian Venetian explorer Sebastian Cabot dispatches his flagship, Trinidad, back to Spain with reports and evidence against the mutineers, and a request for further military aid.[11]
August 4 – The "Peace of St. Ambrose" is signed in Milan at the Basilica of Sant'Ambrogio, bringing an end to the civil strife between the Milanese nobility and the local merchants.
August 29 – The Siege of Naples, at the time a part of the Holy Roman Empire, fails four months after it was launched by troops from France, led by Odet de Foix, who had died of illness on August 15. The Imperial, Spanish and Genoese armies pursue their French attackers, who were attempting to retreat to the nearby city of Aversa, and eliminate the survivors.[13]
September 3 – The Kyōrokuera begins in Japan, with the last day of the Daiei era ending on Daiei 8, 20th day of the 8th month.
September 19 – War of the League of Cognac: The Italian city of Pavia is besieged for the fifth and last time during the decade, after having been attacked in 1522, 1524, 1527, and in May of 1528. Troops from a coalition of the Venetian Republic, the Kingdom of France and the Duchy of Milan break through the city walls after six days of bombardment, kill 700 of the defenders, and recover the city for Francesco II Sforza, Duke of Milan.[14]
October 13 – Cardinal Thomas Wolsey founds a college in his birthplace of Ipswich, England, which becomes the modern-day Ipswich School (incorporating institutions in the town dating back to 1299).
November 6 – Spanish conquistador Álvar Núñez Cabeza de Vaca and his companions become the first known Europeans to set foot on the shores of what is present-day Texas, when they and 80 survivors are wrecked on Galveston Island following a storm.[15] Only 15 live beyond winter, and they are eventually enslaved by various Indian tribes. Eventually, only four of the 81 Spanish survivors— Cabeza de Vaca, Andrés Dorantes de Carranza, Alonso del Castillo Maldonado, and an African slave of Dorantes, Estevanico— are able to escape and return home.[16][17]
^Dylewski, Adam (2011). Historia pieniądza na ziemiach polskich. Warszawa (Warsaw): CARTA BLANCA Sp. z o.o. Grupa Wydawnicza PWN. p. 161. ISBN978-83-7705-068-2.
^Heather Dalton, Merchants and Explorers: Roger Barlow, Sebastian Cabot, & Networks of Atlantic Exchange 1500-1560 (Oxford University Press, 2016), pp. 106-107
^Adorno, Rolena; Pautz, Patrick (September 15, 1999). Álvar Núñez Cabeza de Vaca: His Account, His Life, and the Expedition of Panfilo de Narváez. Lincoln: University of Nebraska Press. ISBN978-0-8032-1463-7., 3 vols.
^Chipman, Donald E. (June 15, 2010). "Malhado Island". TSHA Handbook of Texas Online. Texas State Historical Association.
