The 2006 Eastern League season began on approximately April 1 and the regular season ended on approximately September 1.
The Portland Sea Dogs defeated the Akron Aeros 3 games to 2 to win the Eastern League Championship Series.
| Eastern League - Northern Division | ||||
|---|---|---|---|---|
| Team | Win | Loss | % | GB |
| Trenton Thunder | 80 | 62 | .563 | – |
| Portland Sea Dogs | 72 | 67 | .518 | 6.5 |
| Binghamton Mets | 70 | 70 | .500 | 9.0 |
| New Hampshire Fisher Cats | 68 | 73 | .482 | 11.5 |
| Connecticut Defenders | 64 | 77 | .454 | 15.5 |
| New Britain Rock Cats | 64 | 78 | .451 | 16.0 |
| Eastern League - Southern Division | ||||
|---|---|---|---|---|
| Team | Win | Loss | % | GB |
| Akron Aeros | 87 | 55 | .613 | – |
| Altoona Curve | 75 | 64 | .540 | 10.5 |
| Reading Phillies | 71 | 69 | .507 | 15.0 |
| Bowie Baysox | 67 | 74 | .475 | 19.5 |
| Harrisburg Senators | 67 | 75 | .472 | 20.0 |
| Erie SeaWolves | 60 | 81 | .426 | 26.5 |
Notes:
| Stat | Player | Total |
|---|---|---|
| AVG | Jose Reyna (Trenton Thunder) | .332 |
| HR | Chip Cannon (New Hampshire Fisher Cats) | 27 |
| RBI | Randy Ruiz (Trenton Thunder) | 87 |
| R | Brad Snyder (Akron Aeros) | 86 |
| Stat | Player | Total |
|---|---|---|
| W | Adam Miller (Akron Aeros) | 15 |
| ERA | Phil Hughes (Trenton Thunder) | 2.25 |
| SO | Tyler Clippard (Trenton Thunder) | 175 |
| SV | Brandon Knight (Altoona Curve) | 27 |
The Portland Sea Dogs defeated the Trenton Thunder in the Northern Division playoffs 3 games to 1.
The Akron Aeros defeated the Altoona Curve in the Southern Division playoffs 3 games to 2.
The Portland Sea Dogs defeated the Akron Aeros in the ELCS 3 games to 2.
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