4 January - The University Transition Test that replaced the PSU is carried out, with fewer questions and with a strict health protocol due to the pandemic.
7 January – Former GOPE sergeant Carlos Alarcón is found guilty of the murder of Camilo Catrillanca.[1] A few days later he is sentenced to 16 years in prison.[2]
30 January – A fire at San Borja Arriarán hospital in Santiago required 20 companies of firefighters to control, but the patients were all safely evacuated to nearby hospitals.[3]
5 February – Hundreds protest and municipal buildings are set on fire in Panguipulli after police kill a street performer.[4]
10 February – The government announces it will deport 2,000 undocumented immigrants, mostly from Venezuela. The town of Colchane, Tamarugal Province, has expanded from a population of 300 to 1,700 since 1 February.[5]
11 February – Mónica Zalaquett, Minister of Women and Gender Equity, condemns comments by councilor Iván Roca (Independent Democratic Union) of Lota, Biobío Region, excusing his 33-year-old son′s rape of a 12-year-old girl because the girl had ″the body of a woman″.[6]
15 February – COVID-19: 779,541 total cases since the outbreak of the pandemic, 19,624 deaths, 2,147,272 doses of vaccine administered[7]
21 November – Scheduled date for the 2021 Chilean general election, to elect the President and National Congress. In the 2021 elections 27 members of the Senate (out of a total of maximum 50) will be elected, replacing 20 outgoing senators.[10]