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| Names | |||
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| Preferred IUPAC name
1-Bromo-4-methoxybenzene | |||
| Other names
4-Bromoanisole; para-Bromoanisole; p-Bromoanisole | |||
| Identifiers | |||
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3D model (JSmol) |
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| ChEBI | |||
| ChemSpider |
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| ECHA InfoCard | 100.002.957 
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PubChem CID |
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| UNII | |||
CompTox Dashboard (EPA) |
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| Properties | |||
| C7H7BrO | |||
| Molar mass | 187.036 g·mol−1 | ||
| Density | 1.49 g/ml | ||
| Melting point | 10 °C (50 °F; 283 K) | ||
| Boiling point | 223 °C (433 °F; 496 K) | ||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |||
4-Bromoanisole is the organobromine compound with the formula CH3OC6H4Br. It is colorless liquid with a pleasant smell similar to that of anise seed. It is one of three isomers of bromoanisole, the others being 3-bromoanisole and 2-bromoanisole. It is the precursor to many 4-anisyl derivatives.
4-Bromoanisole forms a Grignard reagent,[1] which reacts with phosphorus trichloride to give tris(4-methoxyphenyl)phosphine:
4-Bromoanisole forms the organozinc derivative CH3OC6H4ZnBr.[2]
4-Bromoanisole is compound sometimes used in RNA extraction which serves to further eliminate DNA contamination.[3] It interacts with genomic DNA (gDNA) and through a separation phase, it will be located in the organic layer instead of the aqueous layer (upper layer) containing the RNA extract.[4]
