Names | |
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Preferred IUPAC name
(1R,3S)-1-(Aminomethyl)-3-phenyl-3,4-dihydro-1H-2-benzopyran-5,6-diol | |
Identifiers | |
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3D model (JSmol) |
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ChEMBL | |
ChemSpider |
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MeSH | A+68930 |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C16H17NO3 | |
Molar mass | 271.316 g·mol−1 |
log P | 1.175 |
Acidity (pKa) | 9.491 |
Basicity (pKb) | 4.506 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
A-68930 is a synthetic compound that acts as a selective dopamine receptor D1 agonist.[1][2] It is orally active and has antidepressant and anorectic effects in animals, producing wakefulness and tachycardia,[3][4][5][6] but without stimulant effects, instead producing sedation.[7][8] The difference in effects between A-68930 and other D1 agonists such as SKF-82958 may be due to their differing effects on the related D5 receptor.[9]
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