Jump to content
 







Main menu
   


Navigation  



Main page
Contents
Current events
Random article
About Wikipedia
Contact us
Donate
 




Contribute  



Help
Learn to edit
Community portal
Recent changes
Upload file
 








Search  

































Create account

Log in
 









Create account
 Log in
 




Pages for logged out editors learn more  



Contributions
Talk
 



















Contents

   



(Top)
 


1 See also  





2 References  





3 Further reading  





4 External links  














ANP32D






العربية
مصرى
Татарча / tatarça
Українська
 

Edit links
 









Article
Talk
 

















Read
Edit
View history
 








Tools
   


Actions  



Read
Edit
View history
 




General  



What links here
Related changes
Upload file
Special pages
Permanent link
Page information
Cite this page
Get shortened URL
Download QR code
Wikidata item
 




Print/export  



Download as PDF
Printable version
 
















Appearance
   

 






From Wikipedia, the free encyclopedia
 


ANP32D
Identifiers
AliasesANP32D, PP32R2, acidic nuclear phosphoprotein 32 family member D
External IDsOMIM: 606878; GeneCards: ANP32D; OMA:ANP32D - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_012404

n/a

RefSeq (protein)

NP_036536

n/a

Location (UCSC)Chr 12: 48.47 – 48.47 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Acidic leucine-rich nuclear phosphoprotein 32 family member D is a protein that in humans is encoded by the ANP32D gene.[3][4][5]

Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is absent in the protein encoded by this gene. This gene does not contain introns.[5]

See also[edit]

References[edit]

  • ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  • ^ Kadkol SS, Brody JR, Pevsner J, Bai J, Pasternack GR (Apr 1999). "Modulation of oncogenic potential by alternative gene use in human prostate cancer". Nat Med. 5 (3): 275–9. doi:10.1038/6488. PMID 10086381. S2CID 24559649.
  • ^ Brody JR, Kadkol SS, Mahmoud MA, Rebel JM, Pasternack GR (Aug 1999). "Identification of sequences required for inhibition of oncogene-mediated transformation by pp32". J Biol Chem. 274 (29): 20053–5. doi:10.1074/jbc.274.29.20053. PMID 10400610.
  • ^ a b "Entrez Gene: ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D".
  • Further reading[edit]

  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Kadkol SS, El Naga GA, Brody JR, et al. (2002). "Expression of pp32 gene family members in breast cancer". Breast Cancer Res. Treat. 68 (1): 65–73. doi:10.1023/A:1017919507109. PMID 11678310. S2CID 11915912.
  • Bai J, Brody JR, Kadkol SS, Pasternack GR (2001). "Tumor suppression and potentiation by manipulation of pp32 expression". Oncogene. 20 (17): 2153–60. doi:10.1038/sj.onc.1204294. PMID 11360199. S2CID 8755931.
  • Kadkol SS, Brody JR, Pevsner J, et al. (1999). "Correction to "Modulation of oncogenic potential by alternative gene use in human prostate cancer"". Nat. Med. 5 (9): 1087. doi:10.1038/12530. PMID 10471270.

  • External links[edit]

  • t
  • e

  • Retrieved from "https://en.wikipedia.org/w/index.php?title=ANP32D&oldid=1142721555"

    Categories: 
    Genes on human chromosome 12
    Human chromosome 12 gene stubs
    Hidden categories: 
    Articles with short description
    Short description matches Wikidata
    All stub articles
     



    This page was last edited on 4 March 2023, at 00:55 (UTC).

    Text is available under the Creative Commons Attribution-ShareAlike License 4.0; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization.



    Privacy policy

    About Wikipedia

    Disclaimers

    Contact Wikipedia

    Code of Conduct

    Developers

    Statistics

    Cookie statement

    Mobile view



    Wikimedia Foundation
    Powered by MediaWiki