Rho guanine nucleotide exchange factor 2 is a protein that in humans is encoded by the ARHGEF2 gene.[5][6][7]
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals.[7]
ARHGEF2 has been shown to interact with PAK1.[8]
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