Adenoma sebaceum, also known as facial angiofibroma is a misnamed cutaneous disorder consisting of angiofibromas that begin in childhood (generally present between 2–5 years of age) and appear clinically as red papules on the face especially on the nasolabial folds, cheek and chin,[1]: 195 often misidentified as acne not responding to treatment. Adenoma sebaceum may at times be associated with tuberous sclerosis.[2] Gradually the papules become more prominent with time and persist throughout life.[3] Cosmetic removal by argonorpulse dye laser or scalpel is indicated.
Adenoma sebaceum are several tiny, pinkish, erythematoushamartomas that cover the nose and cheeks in a distinctive butterfly pattern during early childhood or infancy.[4][5] They typically occur in the nasolabial folds and are symmetrical.[6]
^Hemady, Nikhil; Ohri, Sameer (2009-01-01). "Papulonodular lesions in a man with seizures and mental retardation. Adenoma sebaceum". American Family Physician. 79 (1): 48, 51. ISSN0002-838X. PMID19145966.
^Schwartsmann, G.; Peters, G. J.; Laurensse, E.; de Waal, F. C.; Loonen, A. H.; Leyva, A.; Pinedo, H. M. (1988-09-01). "DUP 785 (NSC 368390): schedule-dependency of growth-inhibitory and antipyrimidine effects". Biochemical Pharmacology. 37 (17): 3257–3266. doi:10.1016/0006-2952(88)90636-3. ISSN0006-2952. PMID2840910.
