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Names | |
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IUPAC name
1-Methylsarpagan-17-ol | |
Systematic IUPAC name
[(6S,9E,10R,11R,12S)-9-Ethylidene-5-methyl-5,6,7,8,9,10,11,11a,12-decahydro-6,10-methanoindolo[2,3-g]quinolizin-11-yl]methanol | |
Other names
De(hydroxymethyl)voachalotinol | |
Identifiers | |
3D model (JSmol) |
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ChemSpider | |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C20H24N2O | |
Molar mass | 308.425 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Affinisine is a monoterpenoid indole alkaloid which can be isolated from plants of the genus Tabernaemontana.[1][2] Structurally, it can be considered a member of the sarpagine alkaloid family and may be synthesized from tryptophan via a Pictet-Spengler reaction.[3][4]
Limited pharmacological testing has indicated that affinisine may effectively inhibit acetylcholinesterase and butyrylcholinesterase.[1][5]
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