| Alpha operon ribosome binding site | |
|---|---|
Predicted secondary structure and sequence conservation of Alpha_RBS
| |
| Identifiers | |
| Symbol | Alpha_RBS |
| Rfam | RF00140 |
| Other data | |
| RNA type | Cis-reg |
| Domain(s) | Bacteria |
| SO | SO:0000233 |
| PDB structures | PDBe |
The alpha operon ribosome binding site in bacteria is surrounded by this complex pseudoknotted RNA structure. Translation of the mRNA produces 4 ribosomal protein products, one of which (S4) acts as a translational repressor by binding to the nested pseudoknot region. The mechanism of repression is thought to involve a conformational switch in the pseudoknot region and ribosome entrapment.[1]
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