Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 is an enzyme that in humans is encoded by the B3GAT3 gene.[5][6]
The protein encoded by this gene is a member of the glucuronyltransferase gene family, enzymes that exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product catalyzes the formation of the glycosaminoglycan-protein linkage by way of a glucuronyl transfer reaction in the final step of the biosynthesis of the linkage region of proteoglycans.[6]
PDB gallery
| |
---|---|
1fgg: CRYSTAL STRUCTURE OF 1,3-GLUCURONYLTRANSFERASE I (GLCAT-I) COMPLEXED WITH GAL-GAL-XYL, UDP, AND MN2+
1kws: CRYSTAL STRUCTURE OF BETA1,3-GLUCURONYLTRANSFERASE I IN COMPLEX WITH THE ACTIVE UDP-GLCUA DONOR
|
| |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
2.4.1: Hexosyl- transferases |
| ||||||||||
2.4.2: Pentosyl- transferases |
| ||||||||||
2.4.99: Sialyl transferases |
|
![]() | This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it. |