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BEX4

Mammalian protein found in humans

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BEX4
Identifiers
Aliases	BEX4, BEXL1, brain expressed X-linked 4
External IDs	OMIM: 300692; MGI: 3606746; HomoloGene: 18948; GeneCards: BEX4; OMA:BEX4 - orthologs
Gene location (Human) Chr. X chromosome (human)[1] Band Xq22.1 Start 103,215,108 bp[1] End 103,217,246 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X F1|X Start 135,039,745 bp[2] End 135,041,192 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prefrontal cortex Brodmann area 9 frontal pole nucleus accumbens C1 segment hypothalamus caudate nucleus pons amygdala right frontal lobe Top expressed in yolk sac epiblast ovary embryo ventricular zone lens mesencephalon neural tube embryo islet of Langerhans More reference expression data BioGPS n/a
Gene ontology Molecular function histone deacetylase binding alpha-tubulin binding Cellular component nucleus cytoplasm microtubule spindle pole cytoskeleton Biological process chromosome segregation regulation of cell migration regulation of cell population proliferation negative regulation of tubulin deacetylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 56271 406217 Ensembl ENSG00000102409 ENSMUSG00000047844 UniProt Q9NWD9 Q9CWT2 RefSeq (mRNA) NM_001127688 NM_001080425 NM_212457 NM_001359569 NM_001359570 RefSeq (protein) NP_001073894 NP_001121160 NP_997622 NP_001346498 NP_001346499 Location (UCSC) Chr X: 103.22 – 103.22 Mb Chr X: 135.04 – 135.04 Mb PubMed search [3] [4]
Wikidata
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Brain expressed, X-linked 4 is a protein that in humans is encoded by the BEX4 gene.^[5]

This gene is a member of the brain expressed X-linked gene family. Proteins encoded by other members of this family act as transcription elongation factors that allow RNA polymerase II to escape pausing during elongation. Multiple alternatively spliced variants encoding the same protein have been identified.^[5]

References[edit]

Further reading[edit]

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