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BRL-54443






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From Wikipedia, the free encyclopedia
  

BRL-54443
Identifiers

  • 3-(1-methylpiperidin-4-yl)-1H-indol-5-ol

CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC14H18N2O
Molar mass230.311 g·mol−1
3D model (JSmol)

  • Oc3ccc1c(c(c[nH]1)C2CCN(C)CC2)c3

  • InChI=1S/C14H18N2O/c1-16-6-4-10(5-7-16)13-9-15-14-3-2-11(17)8-12(13)14/h2-3,8-10,15,17H,4-7H2,1H3 ☒N

  • Key:WKNFADCGOAHBPG-UHFFFAOYSA-N ☒N

 ☒NcheckY (what is this?)  (verify)

BRL-54443 is a drug which acts as a selective agonist for the 5-HT1E and 5-HT1F serotonin receptor subtypes.[1][2]

References[edit]

  1. ^ McKune CM, Watts SW (April 2001). "Characterization of the serotonin receptor mediating contraction in the mouse thoracic aorta and signal pathway coupling". The Journal of Pharmacology and Experimental Therapeutics. 297 (1): 88–95. PMID 11259531.
  • ^ Janssen P, Tack J, Sifrim D, Meulemans AL, Lefebvre RA (May 2004). "Influence of 5-HT1 receptor agonists on feline stomach relaxation". European Journal of Pharmacology. 492 (2–3): 259–67. doi:10.1016/j.ejphar.2004.03.054. PMID 15178373.



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    • Retrieved from "https://en.wikipedia.org/w/index.php?title=BRL-54443&oldid=1075460514"
    Categories: 
    ●5-HT1E agonists
     ●5-HT1F agonists
     ●Indoles
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    ●This page was last edited on 5 March 2022, at 22:36 (UTC).
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