Kane began to act with a small role in the movie Six Weeks. At the age of eight, he obtained the role of one of the four chorus boys in the Broadway musical Evita. He was in that production for four months before changing to the pre-Broadway workshop of Stephen Sondheim's Sunday in the Park with George, in which he acted alongside such stars as Bernadette Peters and Mandy Patinkin. When he was eleven, Kane participated in the "Very Special Arts" festival, a series of benefit concerts for disabled children's charities, which gave him an opportunity to sing for then First Lady Nancy Reagan in the White House and at the Kennedy Center.
In 1993, he played Arpad Laszlo in the Broadway revival of She Loves Me. He also played Tucker Wells in the season three episode "The Prom" of Buffy the Vampire Slayer, and provided Jonathan Levinson's singing voice in the episode "Superstar". On September 11, 2005, Kane was invited to a ceremony at Hong Kong Disneyland, the night before the theme park's opening. He performed the song "A Whole New World" from Aladdin with Cantopop star Joey Yung. As Caleb Kane, he released the song "This Close", which was played on the movie Devil's Pond. Then in 2004, he released his website with a message board to promote his album This Day in History with the first single "Go Mad" released in March 2006. Caleb has two versions of the video of this single and also another promotional video for "In Your Own Way", a song that was played on the show The Black Donnellys.
His first album, This Day in History, was released on July 1, 2008.[3] In Fall 2008, he joined the FOX science-fiction series Fringe as a writer and co-producer. After the completion of the second season, he left the show. He co-wrote the episodes: "The Cure" (co-written by co-executive producer Felicia D. Henderson), "The No-Brainer" (co-written by co-executive producer David H. Goodman), and "Inner Child" (co-written with Julia Cho). On June 7, 2011, it was announced that he was involved with the aborted reboot of Daredevil.[4] Since 2014 Kane is a producer on Black Sails.[5][6]
In 2018, Kane released a collection of ten songs on his Soundcloud site called NEGATIVE PICKUP. The project was abandoned by Kane, only releasing three songs. He has since retired from recording music professionally.[7]
