Contents

CACNB3

Protein-coding gene in humans

CACNB3
Identifiers
Aliases	CACNB3, CAB3, CACNLB3, calcium voltage-gated channel auxiliary subunit beta 3
External IDs	OMIM: 601958; MGI: 103307; HomoloGene: 20187; GeneCards: CACNB3; OMA:CACNB3 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q13.12 Start 48,813,794 bp[1] End 48,828,941 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15 F1|15 54.64 cM Start 98,528,721 bp[2] End 98,542,410 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence frontal pole right uterine tube right frontal lobe right ovary left ovary right hemisphere of cerebellum endothelial cell prefrontal cortex stromal cell of endometrium Top expressed in habenula superior frontal gyrus primary visual cortex entorhinal cortex dentate gyrus of hippocampal formation granule cell perirhinal cortex CA3 field olfactory epithelium lumbar spinal ganglion external carotid artery More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein kinase binding voltage-gated ion channel activity voltage-gated calcium channel activity high voltage-gated calcium channel activity calcium channel activity protein binding calcium channel regulator activity Cellular component apical plasma membrane membrane cytosol plasma membrane voltage-gated calcium channel complex L-type voltage-gated calcium channel complex cytoplasm Biological process membrane depolarization regulation of ion transmembrane transport ion transport regulation of voltage-gated calcium channel activity neuromuscular junction development calcium ion transmembrane transport calcium ion transport regulation of membrane repolarization during action potential calcium ion transport into cytosol protein localization to plasma membrane chemical synaptic transmission calcium ion transmembrane transport via high voltage-gated calcium channel detection of mechanical stimulus involved in sensory perception of pain positive regulation of protein targeting to membrane cellular response to oxygen-glucose deprivation negative regulation of voltage-gated calcium channel activity positive regulation of voltage-gated calcium channel activity positive regulation of high voltage-gated calcium channel activity regulation of membrane hyperpolarization negative regulation of detection of mechanical stimulus involved in sensory perception of touch positive regulation of excitatory postsynaptic potential T cell receptor signaling pathway cardiac conduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 784 12297 Ensembl ENSG00000167535 ENSMUSG00000003352 UniProt P54284 P54285 RefSeq (mRNA) NM_000725 NM_001206915 NM_001206916 NM_001206917 NM_001044741 NM_001286226 NM_007581 NM_001356543 RefSeq (protein) NP_000716 NP_001193844 NP_001193845 NP_001193846 NP_001038206 NP_001273155 NP_031607 NP_001343472 Location (UCSC) Chr 12: 48.81 – 48.83 Mb Chr 15: 98.53 – 98.54 Mb PubMed search [3] [4]
Wikidata
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Voltage-dependent L-type calcium channel subunit beta-3 is a protein that in humans is encoded by the CACNB3 gene.^[5][6]

• Voltage-dependent calcium channel

• CACNB3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
• Human CACNB3 genome location and CACNB3 gene details page in the UCSC Genome Browser.

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