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CLCC1

From Wikipedia, the free encyclopedia
CLCC1
Identifiers
AliasesCLCC1, MCLC, chloride channel CLIC like 1
External IDsOMIM: 617539; MGI: 2385186; HomoloGene: 9032; GeneCards: CLCC1; OMA:CLCC1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015127
NM_001048210
NM_001278202
NM_001278203

NM_001177770
NM_001177771
NM_145543
NM_001355632

RefSeq (protein)

NP_001171241
NP_001171242
NP_663518
NP_001342561

Location (UCSC)Chr 1: 108.93 – 108.96 MbChr 3: 108.56 – 108.59 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Chloride channel CLIC-like 1 also known as CLCC1 is a human gene.[5][6]

The protein encoded by this gene is a chloride channel which is related in sequence to the S. cerevisiae MID-1 stretch-activated channel. CLCC1 is located in the membranes of intracellular compartments including endoplasmic reticulum and the Golgi apparatus. It is highly expressed in the testis and moderately in the spleen, liver, kidney, heart, brain, and lung.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000121940Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027884Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (October 1998). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
  6. ^ a b Nagasawa M, Kanzaki M, Iino Y, Morishita Y, Kojima I (June 2001). "Identification of a novel chloride channel expressed in the endoplasmic reticulum, golgi apparatus, and nucleus". J. Biol. Chem. 276 (23): 20413–8. doi:10.1074/jbc.M100366200. PMID 11279057.

Further reading

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