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| Names | |
|---|---|
| Preferred IUPAC name
2-Chloroacetamide | |
| Identifiers | |
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3D model (JSmol) |
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| ChEBI | |
| ChemSpider | |
| ECHA InfoCard | 100.001.068 
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| EC Number |
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PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| ClCH2CONH2 | |
| Molar mass | 93.51 g·mol−1 |
| Appearance | Colorless crystals or white fine powder[1] (yellow if impure) |
| Odor | Characteristic |
| Density | 1.58 g/cm3 at 20 °C[1] |
| Melting point | 120 °C (248 °F; 393 K) |
| |
| Vapor pressure | 0.07 hPa at 20 °C[1] |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards |
Very toxic. It is suspected of reproductive toxicity and teratogenicity. |
Ingestion hazards |
Very toxic |
Inhalation hazards |
Very toxic |
Eye hazards |
Irritation |
Skin hazards |
Irritation |
| GHS labelling: | |
 
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| Danger | |
| H301, H317, H361, H402 | |
| P201, P202, P261, P264, P270, P272, P273, P280, P301+P310+P330, P302+P352, P308+P313, P333+P313, P405, P501 | |
| Flash point | 170 °C (338 °F; 443 K) |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
138 mg/kg (oral, rat) >2000 mg/kg (skin, rat) |
LC50 (median concentration) |
19.8 mg/l, 96 h (Carassius auratus (goldfish)) |
| Safety data sheet (SDS) | [1] |
| Related compounds | |
Related compounds |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chloroacetamide (2-chloroacetamide) is a chlorinated organic compound with the molecular formula ClCH2CONH2. It is a colorless solid although older samples appear yellow. It has a characteristic odor and is readily solubleinwater.[2] It has the structure Cl−CH2−C(=O)−NH2.
Chloroacetamide is produced by ammonolysisofestersofchloroacetic acid:[3][4]
Chloroacetamide has been used as an herbicide,[5] preservative.[6] and in the manufacturing of pharmaceuticals.
Chloroacetamide is toxic, irritates eyes and skin, and may cause an allergic reaction. It is suspected of reproductive toxicity and teratogenicity.[7]
