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(Top) 1 Synthesis 2 See also 3 References

Cicloprolol

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Cicloprolol
Names

IUPAC name 1-[4-[2-(Cyclopropylmethoxy)ethoxy]phenoxy]-3-(propan-2-ylamino)propan-2-ol
Identifiers
CAS Number	63659-12-1^Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL2110772
ChemSpider	129044
IUPHAR/BPS	552
KEGG	D03490
PubChem CID	146294
UNII	1K2ACH4U3R^Y
CompTox Dashboard (EPA)	DTXSID70867026
InChI InChI=1S/C18H29NO4/c1-14(2)19-11-16(20)13-23-18-7-5-17(6-8-18)22-10-9-21-12-15-3-4-15/h5-8,14-16,19-20H,3-4,9-13H2,1-2H3 Key: JNDJPKHYZWRRIS-UHFFFAOYSA-N
SMILES CC(C)NCC(COC1=CC=C(C=C1)OCCOCC2CC2)O
Properties
Chemical formula	C₁₈H₂₉NO₄
Molar mass	323.433 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Cicloprolol is a beta-adrenoceptor antagonist.^[1]

Synthesis[edit]

Cicloprolol synthesis:^[2]^[3]

References[edit]

^ Cocco, G; Alfiero, R; Pouleur, H (1992). "An evaluation of the safety of the beta-modulator cicloprolol in chronic heart failure". Clinical Cardiology. 15 (1): 38–42. doi:10.1002/clc.4960150109. PMID 1347258.

^ DE 2649605, Manoury, Philippe Michel Jacques; Cavero, Icilio Angelo Girolamo & Majer, Henry et al., "Phenoläther, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimttel [Phenol ethers, processes for their preparation and medicinal products containing them]", published 1977-05-18, assigned to Synthelabo S.A.

^ P. M. J. Manouri, I. A. G. Carero, H. Majer, and P. R. L. Giudicelli, (1977) Chem. Abstr., 87:134,543j (1977). eidem U.S. patent 4,311,708