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F r o m W i k i p e d i a , t h e f r e e e n c y c l o p e d i a
Chaim Weizmann
Clostridium acetobutylicum , ATCC 824, is a commercially valuable bacterium sometimes called the "Weizmann Organism ", after Jewish Russian-born biochemist Chaim Weizmann . A senior lecturer at the University of Manchester , England , he used them in 1916 as a bio-chemical tool to produce at the same time, jointly, acetone , ethanol , and n-butanol from starch . The method has been described since as the ABE process , (Acetone Butanol Ethanol fermentation process), yielding 3 parts of acetone , 6 of n -butanol, and 1 of ethanol . Acetone was used in the important wartime task of casting cordite . The alcohols were used to produce vehicle fuels and synthetic rubber .
Unlike yeast , which can digest only some sugars into alcohol and carbon dioxide , C. acetobutylicum and other Clostridia can digest whey , sugar, starch , cellulose and perhaps certain types of lignin , yielding n -butanol, propionic acid , ether , and glycerin .
In genetic engineering
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In 2008, a strain of Escherichia coli was genetically engineered to synthesize butanol; the genes were derived from Clostridium acetobutylicum .[1] [2] In 2013, the first microbial production of short-chain alkanes was reported[3] - which is a considerable step toward the production of gasoline. One of the crucial enzymes - a fatty acyl-CoA reductase - came from Clostridium acetobutylicum .
See also
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References
[ edit ]
^ Choi, YJ.; Lee, SY. (Oct 2013). "Microbial production of short-chain alkanes". Nature . 502 (7472): 571–4. Bibcode :2013Natur.502..571C . doi :10.1038/nature12536 . PMID 24077097 . S2CID 4393929 .
Further reading
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Nölling J, Breton G, Omelchenko MV, et al. (August 2001). "Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum" . J. Bacteriol . 183 (16 ): 4823–38. doi :10.1128/JB.183.16.4823-4838.2001 . PMC 99537 . PMID 11466286 .
Driessen AJ, Ubbink-Kok T, Konings WN (February 1988). "Amino acid transport by membrane vesicles of an obligate anaerobic bacterium, Clostridium acetobutylicum" . J. Bacteriol . 170 (2 ): 817–20. doi :10.1128/jb.170.2.817-820.1988 . PMC 210727 . PMID 2828326 .
Zappe H, Jones WA, Jones DT, Woods DR (May 1988). "Structure of an endo-beta-1,4-glucanase gene from Clostridium acetobutylicum P262 showing homology with endoglucanase genes from Bacillus spp" . Appl. Environ. Microbiol . 54 (5 ): 1289–92. Bibcode :1988ApEnM..54.1289Z . doi :10.1128/AEM.54.5.1289-1292.1988 . PMC 202643 . PMID 3389820 .
Bowles LK, Ellefson WL (November 1985). "Effects of butanol on Clostridium acetobutylicum" . Appl. Environ. Microbiol . 50 (5 ): 1165–70. Bibcode :1985ApEnM..50.1165B . doi :10.1128/AEM.50.5.1165-1170.1985 . PMC 238718 . PMID 2868690 .
US 1875536
US 1315585
Weber, Christian; Farwick, Alexander; Benisch, Feline; Brat, Dawid; Dietz, Heiko; Subtil, Thorsten; Boles, Eckhard (10 June 2010). "Trends and challenges in the microbial production of lignocellulosic bioalcohol fuels". Applied Microbiology and Biotechnology . 87 (4 ): 1303–1315. doi :10.1007/s00253-010-2707-z . ISSN 0175-7598 . PMID 20535464 . S2CID 12601202 .
Jones, DT; Woods, DR (1986). "Acetone-butanol fermentation revisited" . Microbiological Reviews . 50 (4 ): 484–524. doi :10.1128/MMBR.50.4.484-524.1986 . PMC 373084 . PMID 3540574 .
Bartha, Ronald M. Atlas & Richard (1993). Microbial ecology : fundamentals and applications (3rd ed.). Redwood City, Calif.: Benjamin/Cummings Pub. Co. p. 563 . ISBN 978-0-8053-0653-8 .
Microbial Processes: Promising Technologies for Developing Countries . Washington: National Academy of Sciences. 1979. doi :10.17226/9544 . ISBN 978-0-309-57050-3 . Retrieved 10 May 2011 .
Wong Kromhout, Wileen (2011-03-16). "UCLA researchers engineer E. coli to produce record-setting amounts of alternative fuel" . UCLA Newsroom . Archived from the original on 2015-04-18. Retrieved 2015-04-18 .
External links
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Clostridium acetobutylicum
R e t r i e v e d f r o m " https://en.wikipedia.org/w/index.php?title=Clostridium_acetobutylicum&oldid=1181908068 "
C a t e g o r i e s :
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● T h i s p a g e w a s l a s t e d i t e d o n 2 5 O c t o b e r 2 0 2 3 , a t 2 3 : 1 8 ( U T C ) .
● T e x t i s a v a i l a b l e u n d e r t h e C r e a t i v e C o m m o n s A t t r i b u t i o n - S h a r e A l i k e L i c e n s e 4 . 0 ;
a d d i t i o n a l t e r m s m a y a p p l y . B y u s i n g t h i s s i t e , y o u a g r e e t o t h e T e r m s o f U s e a n d P r i v a c y P o l i c y . W i k i p e d i a ® i s a r e g i s t e r e d t r a d e m a r k o f t h e W i k i m e d i a F o u n d a t i o n , I n c . , a n o n - p r o f i t o r g a n i z a t i o n .
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