| CopA-like RNA | |
|---|---|
Predicted secondary structure and sequence conservation of CopA
| |
| Identifiers | |
| Symbol | CopA |
| Rfam | RF00042 |
| Other data | |
| RNA type | Gene; antisense |
| Domain(s) | Bacteria |
| SO | SO:0000644 |
| PDB structures | PDBe |
CopA-like RNA is a family of non-coding RNAs found on the R1 plasmid.
In several groups of bacterial plasmids, antisense RNAs regulate copy number through inhibition of replication initiator protein synthesis. These RNAs are characterised by a long hairpin structure interrupted by several unpaired nucleotides or bulged loops. In plasmid R1, the inhibitory complex between the antisense RNA (CopA) and its target mRNA (CopT) is characterised by a four-way junction structure and a side-by-side helical alignment.[1][2][3]
Plasmid-mediated resistance (sRNA section)
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