Diacylglycerol kinase zeta is an enzyme that in humans is encoded by the DGKZ gene.[5][6]
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.[6]
DGKZ has been shown to interact with P110α.[7]
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