DPD scanning typically uses a gamma camera to obtain SPECT images, with an injection followed by an initial scan after 5 minutes, and a second scan after 3 hours.[3]
Images are often scored using the "Perugini system" whereby:[4][5]
Grade 0 – no cardiac uptake and normal bone uptake
Grade 1 – cardiac uptake which is less intense than the bone signal
Grade 2 – cardiac uptake with intensity similar or greater than bone signal
Grade 3 – cardiac uptake with much attenuated or absent bone signal
^"Amyloidosis Overview". Centre for Amyloidosis and Acute Phase Proteins. University College London. 22 May 2018. Retrieved 27 June 2019.
^Perugini, Enrica; Guidalotti, Pier Luigi; Salvi, Fabrizio; et al. (September 2005). "Noninvasive Etiologic Diagnosis of Cardiac Amyloidosis Using 99m Tc-3,3-Diphosphono-1,2-Propanodicarboxylic Acid Scintigraphy". Journal of the American College of Cardiology. 46 (6): 1076–1084. doi:10.1016/j.jacc.2005.05.073. PMID16168294.
