Names
N-[(2-Bromophenyl)methyl]-2-chloro-N-ethylethan-1-amine
Identifiers
3D model (JSmol)
PubChem CID
CompTox Dashboard (EPA)
InChI=1S/C11H15BrClN/c1-2-14(8-7-13)9-10-5-3-4-6-11(10)12/h3-6H,2,7-9H2, 1H3
Key: SDJLVPMBBFRBLL-UHFFFAOYSA-N
CCN(CCCl)CC1=CC=CC=C1Br
Properties
C11H15BrClN
276.60 g/mol
1.339 g/cm3
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
DSP-4, or N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine, is a neurotoxin selective for noradrenergic neurons, capable of crossing the blood–brain barrier.[1]
It exerts transient effects in peripheral sympathetic neurons, but more permanent changes within neurons of the central nervous system. It can induce long-term depletion in cortical and spinal levels of noradrenaline.[2]
Other