While at Lilly, Wong became most interested in agents that bind to Biogenic Amine Transporters (BAT). These compounds primarily affect functioning of the CNS and have known uses in the treatment of depression, ADHD, libido, obesity and addiction. Although such agents can be made to increase serotonin and norepinephrine, an example of a compound with a demonstrated affinity for the DAT is called N-methylatmoxetine [83015-25-2].[4] He helped to study:
Wong met his wife, Christiana Lee, at the Oregon State University. They are devout Christians, and had three children together: Conrad, Mel, and Vincent Wong.[2]
^Bryan B. Molloy & Klaus K. Schmiegel, U.S. patent 4,584,404 (1986 to Eli Lilly and Co).
^Wong DT, Horng JS, Bymaster FP (September 1975). "dl-N-methyl-3-(o-methoxyphenoxy)-3-phenylpropylamine hydrochloride, Lilly 94939, a potent inhibitor for uptake of norepinephrine into rat brain synaptosomes and heart". Life Sciences. 17 (5): 755–760. doi:10.1016/0024-3205(75)90531-7. ISSN0024-3205. PMID1207394.
^Fuller RW, Wong DT, Snoddy HD, Bymaster FP (July 1977). "Comparison of the effects of 6-chloro-2-aminotetralin and of Org 6582, a related chloroamphetamine analog, on brain serotonin metabolism in rats". Biochemical Pharmacology. 26 (14): 1333–1337. doi:10.1016/0006-2952(77)90094-6. ISSN0006-2952.
^Mitch, C. H., Leander, J. D., Mendelsohn, L. G., Shaw, W. N., Wong, D. T., Cantrell, B. E., Johnson, B. G., Reel, J. K., Snoddy, J. D. (October 1993). "3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines: opioid antagonists with potent anorectant activity". Journal of Medicinal Chemistry. 36 (20): 2842–2850. doi:10.1021/jm00072a002. eISSN1520-4804. ISSN0022-2623. PMID8410999.
^Wong, D. T., Robertson, D. W., Reid, L. R. (July 1989). "Specific [3H]LY278584 binding to 5-HT3 recognition sites in rat cerebral cortex". European Journal of Pharmacology. 166 (1): 107–110. doi:10.1016/0014-2999(89)90689-4. ISSN0014-2999. PMID2806363.
